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Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie +24 more
wiley +1 more source
IntroductionFostering Artificial Intelligence (AI) literacy and equipping college students with 21st-century skills in the generative AI era have become a global educational priority. In this context, generative AI offers opportunities for development in
Reham Salhab, Mosab M. Aboushi
doaj +1 more source
: The high number of job seekers and low-level students who dare to become job creators indicates that the capabilities of vocational students in the fourth industrial revolution era are very low.
Anis Kurniawan +2 more
doaj +1 more source
The study ascertained the profile of students and faculty members and the level of their critical thinking, collaboration, communication, creativity and innovation, self-direction, global connections, local connections skills, and use of technology as a ...
Nancy Ann Pawid Gonzales
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Cost Pass‐Through in Crisis: Evidence From the German Malt‐Beer Supply Chain
Abstract Global agri‐food supply chains are increasingly exposed to geopolitical shocks, climate volatility, and market consolidation, factors that disrupt traditional price relationships and reshape market power dynamics. Nowhere is this more visible than in the brewing sector, where agricultural raw materials meet complex industrial processing and ...
Nikolas Bublik, Lukáš Čechura
wiley +1 more source
The Sequential and Conditional Nature of 21st-Century Digital Skills
The importance of 21st-century digital skills has been well established. However, research often fails to examine how various skills relate to each other. Through a survey of a sample of 1,222 professionals working in the creative industries, we tested,
Ester van Laar +3 more
doaj
ABSTRACT Since the final decade of the 20th century, Latin American countries have increasingly regarded the signing of regional trade agreements (RTAs) as a promising strategy for expanding their exports. Within this context, the main objective of this study is to assess the impact of RTAs on agri‐food exports in Latin America over the period 1990 ...
María‐Isabel Ayuda +2 more
wiley +1 more source
Maker education provides the perfect context for young learners to develop 21st-century skills. However, research is inconclusive on how these skills could be assessed.
Ioannou, Andri +3 more
core +1 more source
Data‐Efficient Cycle‐Level Capacity Prediction Using 1D Deep Convolutional Network
We introduce DeepBat, a deep learning framework featuring a 1D convolutional backbone designed to extract latent degradation patterns from a microstructurally diverse electrode dataset. By learning complex formulation–performance relationships, the model accurately predicts long‐term specific discharge capacity using limited early‐cycle data, providing
Tao Huang +16 more
wiley +1 more source
DEVELOPING 21st CENTURY SKILLS
The industrial revolution 4.0 that occurred in the 21st century has brought about the needs and challenges of life that are different from the previous century. Changes that occur so quickly and are full of disruption due to the development of information technology require mastery of skills relevant to the needs of the 21st century.
openaire +1 more source

