Results 151 to 160 of about 62,546,466 (197)
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25-Hydroxycholecalciferol in experimental osteoporosis
Clinical Rheumatology, 1985The authors, using the experimental pattern of bone rarefaction induced by a low calcium diet, tried to determine if 25-hydroxycholecalciferol, administered at doses and according to procedures similar to those used in osteoporosis, might interfere in such a process of rarefaction.
Carrozzo M +5 more
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Measurement of Plasma 25‐Hydroxycholecalciferol in Man
European Journal of Clinical Investigation, 1972Abstract. A radio‐ligand assay for the measurement of 25‐hydroxycholecalciferol (25‐OH D3) in human plasma has been devised. Three ml of plasma, with 25‐hydroxychole‐calciferol‐26, 27‐H3 (3H‐25‐OH D3) added for recovery, was extracted and purified by thin‐layer chromatography. The plasma from an osteomalacic man, diluted 1 to 800, was used as a source
F, Bayard, P, Bec, J P, Louvet
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25-Hydroxycholecalciferol levels in bedouins in the Negev
The American Journal of Clinical Nutrition, 197625-Hydroxycholecalciferol (25-HCC) levels were measured in 31 bedouin females and eight bedouin male tribesmen and compared with the levels in Jewish males and females in Beersheba. In nonpregnant bedouin women the mean 25-HCC level was 25.4 ng/ml +/- 9.78. In pregnant bedouin women the mean was 23.4 ng/ml +/- 8.52.
S, Shany, J, Hirsh, G M, Berlyne
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Metabolism of 25-Hydroxycholecalciferol in Nephrectomized Rats
Klinische Wochenschrift, 1971Der Metabolismus von 25-Hydroxycholecalciferol wurde in nephrektomierten rachitischen Ratten und in rachitischen Kontroll-Ratten untersucht. Das Stoffwechselmuster war fur beide Gruppen in Blut, Knochen, Leber und in der Darmschleimhaut ahnlich. Insbesondere war auch die Bildung von Peak V, der als ein aktiver Metabolit von Vitamin D angesehen wird ...
K, Schaefer +4 more
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The Influence of Phenobarbital on Biotransformation of 25‐Hydroxycholecalciferol
The Journal of Clinical Pharmacology, 1976Altered vitamin D metabolism has been implicated as a cause of anticonvulsant-induced osteomalacia. Previous studies have demonstrated accelerated biotransformation of vitamin D3 to 25-hydroxycholecalciferol (25-OHD3). However, it is not known whether the 25-OHD3 is metabolized to 1,25-dihydroxycholecalciferol (1,25-(OH)2D3), the tissue-active ...
R, Burt, J W, Freston, K G, Tolman
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Acute Administration of 25-Hydroxycholecalciferol in Man
The Journal of Clinical Endocrinology & Metabolism, 1976Serum 25-hydroxyvitamin D responses to oral doses of 25-hydroxycholecalciferol were measured in healthy volunteers. Peak serum 25-hydroxyvitamin D levels occurred 4 to 8 hours after doses of 1.5, 5, and 10 mug per kg of body weight. The mean increments above baseline serum 25-hydroxyvitamin D concentrations at 4 hours were linear over this dose range ...
J G, Haddad, S, Rojanasathit
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Metabolism of 25-hydroxycholecalciferol by human bone
Journal of Endocrinological Investigation, 1983Although there is abundant evidence from animal studies that 1,25-dihydroxychole-calciferol [1,25-(OH)2D3] is synthesized in the kidney, it is still unknown whether human bone might also be involved in the formation of this metabolite. To investigate whether 1,25-(OH)2D3 can be synthesized by human bone, 25-hydroxycholecalciferol (25-OH D3) metabolism ...
E, Keck +7 more
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25-Hydroxycholecalciferol Metabolism in Hypophysectomized Rats*
Endocrinology, 1978The metabolism of 25-hydroxycholecalciferol (25-(OH)Da) was investigated in vitamin D normal rats, 4 weeks after hypophysectomy. Compared to sham-operated controls, these animals were hypophosphatemic and their parathyroid glands were significantly smaller than normal. Eighteen hours after ip injection of a single dose of tritiated 25-(OH)D3 (50 pmol),
O, Fontaine, H, Pavlovitch, S, Balsan
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Synthesis of [26,27-3H]-25-hydroxycholecalciferol
Analytical Biochemistry, 1971Abstract [26,27- 3 H]-25-HCC has been chemically synthesized. This preparation is radiochemically pure and has a specific activity (180,000 dpm/IU, 1.3 Ci/mmole) high enough to permit experiments with 0.025 μg of 25-HCC/rat. This preparation is biologically as active (52 IU/μg) as either isolated or synthetic 25-HCC in curing rickets in rats.
T, Suda, H F, DeLuca, R B, Hallick
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25-Hydroxycholecalciferol and Fractures of the Proximal Femur
Lancet, The, 1975Abstract Plasma 25-hydroxycholecalciferol (25-H.C.C.) has been measured in 67 consecutive cases of fracture of the proximal femur. The values found in these patients were not different from those in control groups at the same time of the year. Plasma 25-H.C.C.
B Lund, O H Sørensen
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