Observations of Modified Polyps and Polyp Leaves in Sea Pens (Cnidaria: Octocorallia): The Cases of <i>Ptilella</i> and <i>Pennatula</i>. [PDF]
de Moura Neves B +4 more
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Integrative taxonomy of a monopisthocotylan (Platyhelminthes, Neodermata) parasite from the gills of Doras higuchii Sabaj Pérez & Birindelli (Siluriformes, Doradidae) from the Xingú River Basin, Pará, Brazil. [PDF]
Souza ILM +3 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Integrative redescription of Sprostoniella micrancyra Cezar, Luque and Amato, 1999 (Monopisthocotylea: Capsalidae) and the phylogenetic position of Sprostoniella Bychowsky and Nagibina, 1967. [PDF]
Machado AB +5 more
europepmc +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A Prickly Problem: Genome Skimming Reveals Varying Levels of Phylogenetic Diversity in the Freshwater Crayfish <i>Euastacus armatus</i> Complex (Parastacidae) With Implications for Taxonomy and Conservation. [PDF]
Austin CM +11 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

