Identification and Stability Assessment of Reference Genes in Helicoverpa armigera Under Plant Secondary Substance and Insecticide Stresses. [PDF]
Zhao J +6 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Three new species of Macvicaria Gibson & Bray, 1982 (Digenea: Opecoelidae) infecting Diplodus spp. (Teleostei, Sparidae) from South Africa and Namibia. [PDF]
Vermaak A, Kudlai O, Yong RQ, Smit NJ.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Two new species of <i>Tricholomopsis</i> (Agaricales) from China based on molecular phylogenetic and morphological evidence. [PDF]
Wang G +6 more
europepmc +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
A new freshwater snail genus of Squamapicidae (Gastropoda, Truncatelloidea) with a novel posterior respiratory canal unveils an unexpected morphological innovation. [PDF]
Zheng H +8 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Detection and Identification of <i>Paragyliauchen</i> sp. (Trematoda) and Bacteria in Diseased <i>Centropyge bicolor</i> from the European Marine Aquarium Trade. [PDF]
Guz L, Pastuszka A, Torbicz M, Oszust M.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

