Results 71 to 80 of about 23,513,080 (129)

Signatures of Selection for Resistance/Tolerance to Perkinsus olseni in Grooved Carpet Shell Clam (Ruditapes decussatus) Using a Population Genomics Approach

Evolutionary Applications, Volume 18, Issue 5, May 2025.
ABSTRACT The grooved carpet shell clam (Ruditapes decussatus) is a bivalve of high commercial value distributed throughout the European coast. Its production has suffered a decline caused by different factors, especially by the parasite Perkinsus olsenii. Improving production of R.
Inés M. Sambade, João Estêvão, Marina Pampín, Andreia Cruz, Eric Guévélou, Andrés Blanco, Francisco Câmara, Jessica Gómez‐Garrido, Fernando Cruz, Luca Bargelloni, Stefano Carboni, Tyler Alioto, Benjamin Costas, Sergio Fernández‐Boo, Paulino Martínez   +14 more
wiley   +1 more source

The Roles of Bacteria in the Microbiome–Intervertebral Disc Axis

Advanced Gut &Microbiome Research, Volume 2025, Issue 1, 2025.
Several studies have proposed the existence of a gut microbiome–intervertebral disc (IVD) axis. Bacteria found infiltrating the disc space may potentially contribute to IVD degeneration and the generation of low back pain, the number one global musculoskeletal condition of major socioeconomic impact.
James Melrose, Margaret M. Smith, Ashish Diwan, Jiong Yu   +3 more
wiley   +1 more source

Whole exome sequencing in family trios reveals de novo mutations in PURA as a cause of severe neurodevelopmental delay and learning disability [PDF]

, 2014
Background: De novo mutations are emerging as an important cause of neurocognitive impairment, and whole exome sequencing of case-parent trios is a powerful way of detecting them. Here, we report the findings in four such trios.
Baralle, Diana, The DDD study, Swoboda, KJ, Taft, R, Magee, A. C., Swoboda, Kathryn J., Taft, R., Turnpenny, Peter D., Baralle, D., Swodboda, Kathryn J., Baralle, D, Hunt, D, Magee, A.C., Turnpenny, Perter D., Taft, Ryan J., Hunt, David, Gawne-Cain, M, Hunt, D., Turnpenny, P.D., Gawne-Cain, M., Simons, C, Leventer, R. J., D. D. D. study, Simons, C., Gwan-Cain, Mary, Magee, AC, Taft, Ryan, Turnpenny, PD, Swoboda, K. J., Simons, Cas, Gawne-Cain, Mary, Leventer, Richard J., Leventer, R.J., Leventer, RJ, Swoboda, K.J., Magee, Alex C.   +35 more
core   +1 more source

Colorectal cancer-specific microbiome in peripheral circulation and cancer tissues

Frontiers in Microbiology
IntroductionAccumulating evidence has supported that gut microbiota and metabolite profiles play indispensable roles in the pathogenesis of colorectal cancer (CRC), which ranks as the third most common cancer and the second leading cause of cancer ...
Shushan Yan, Shushan Yan, Tie Liu, Haobin Zhao, Chunbo Zhao, Yuxin Zhu, Wenqing Dai, Wenchang Sun, Honggang Wang, Junxi Sun, Lu Zhao, Lu Zhao, Lu Zhao, Donghua Xu, Donghua Xu   +14 more
doaj   +1 more source

Drivers of genomic diversity and phenotypic development in early phases of domestication in Hermetia illucens

Insect Molecular Biology, Volume 33, Issue 6, Page 756-776, December 2024.
Random drift rather than selection is the primary evolutionary force driving genomic and phenotypic variation in BSF populations during early phases of domestication. Functional trade‐offs between production and fitness traits were observed in BSF populations.
Kelvin L. Hull, Matthew P. Greenwood, Melissa Lloyd, Marissa Brink‐Hull, Aletta E. Bester‐van der Merwe, Clint Rhode   +5 more
wiley   +1 more source

Riverscape genomics of the endangered freshwater mussel Lampsilis rafinesqueana

Freshwater Biology, Volume 69, Issue 10, Page 1438-1453, October 2024.
Abstract Historical periods of rapid climate change and associated direct and indirect impacts such as glaciation and restructuring of drainage systems are important in shaping biodiversity, lineage divergence, and contemporary genetic variation amongst many aquatic taxa.
Steven R. Hein, Keaka Farleigh, David J. Berg   +2 more
wiley   +1 more source

Roles of intralesional bacteria in the initiation and progression of oral squamous cell carcinoma

Cancer Medicine, Volume 13, Issue 18, September 2024.
Abstract Background Oral squamous cell carcinoma (OSCC) is the predominant form of head and neck cancer, often diagnosed at late stages, resulting in a poor prognosis. Recent studies indicate a potential association between OSCC and microbial presence.
Zhuoyan Luo, Shiping Lv, Fangzhi Lou, Li Yan, Jingyi Xu, Ning Kang, Yunmei Dong, Xin Jin   +7 more
wiley   +1 more source

Rapid identification of mutations in GJC2 in primary lymphoedema using whole exome sequencing combined with linkage analysis with delineation of the phenotype. [PDF]

, 2011
Background: Primary lymphoedema describes a chronic, frequently progressive, failure of lymphatic drainage. This disorder is frequently genetic in origin, and a multigenerational family in which eight individuals developed postnatal lymphoedema of all ...
Ostergaard, P, Connell, Fiona C., Simpson, MA, S. Mansour, G. Brice, P. S. Mortimer, Connell, FC, Jeffery, S, M. A. Simpson, Child, Anne H., Mansour, S, R. Trembath, F. C. Connell, A. Onoufriadis, Trembath, Richard, Mortimer, Peter S, Mortimer, Peter S., Mansour, Sahar, Kalidas, Kamini, Trembath, R, Brice, Glen, Child, AH, P. Ostergaard, Jeffery, Steve, Mortimer, PS, Ostergaard, Pia, J. Hwang, K. Kalidas, A. H. Child, Hwang, J, Simpson, Michael A, Onoufriadis, A, Connell, Fiona, S. Jeffery, Simpson, Michael A., Brice, G, Hwang, Jae, Kalidas, K, Onoufriadis, Alexandros, Child, Anne H   +39 more
core   +1 more source

Both symbionts and environmental factors contribute to shape the microbiota in a pest insect, Sogatella furcifera

Frontiers in Microbiology
IntroductionBacterial symbionts are prevalent in arthropods globally and play a vital role in the fitness and resistance of hosts. While several symbiont infections have been identified in the white-backed planthopper Sogatella furcifera, the impact of ...
Kun Yang, Kun Yang, Hua-Yue Zhang, Hua-Yue Zhang, Peng Wang, Peng Wang, Gui-Xiu Jin, Dong Chu, Dong Chu   +8 more
doaj   +1 more source

Image_2_Microbial signatures of neonatal bacterial meningitis from multiple body sites.pdf

, 2023
As a common central nervous system infection in newborns, neonatal bacterial meningitis (NBM) can seriously affect their health and growth. However, although metagenomic approaches are being applied in clinical diagnostic practice, there are some ...
Yuyang Hou, Jiang Liu, Jiang Liu (197069), Meng Zhang, Zheng Sun (261083), Yuping Yang (3874810), Xiuxiang Liu (13210893), Qiannan Jiang (16862091), Yuping Yang, Meng Zhang (154027), Ke Yuan (172453), Yuyang Hou (1622695), Zheng Sun, Ke Yuan, Xiuxiang Liu, Qiannan Jiang   +15 more
core   +1 more source