Results 111 to 120 of about 1,083,982 (306)
Efficient radiational outcoupling of electromagnetic energy from hyperbolic metamaterial resonators
Scientific Reports, 2020 Hyperbolic metamaterials were initially proposed in optics to boost radiation efficiencies of quantum emitters. Adopting this concept for antenna design allows approaching long-standing contests in radio physics. For example, broadband impedance matching,
Ildar Yusupov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Absorption $\textit{versus}$ Adsorption: High-Throughput Computation of Impurities in 2D Materials
, 2023 Doping of a two-dimensional (2D) material by impurity atoms occurs \textit{via} two distinct mechanisms: absorption of the dopants by the 2D crystal or adsorption on its surface.
Bertoldo, Fabian +7 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fermi level depinning via insertion of a graphene buffer layer at the gold–2D tin monoxide contact
, 2023 Two-dimensional (2D) tin monoxide (SnO) has attracted much attention owing to its distinctive electronic and optical properties, which render itself suitable as a channel material in field effect transistors (FETs).
Xue, Ming +7 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Safety concerns on graphene and 2D materials: A Flagship perspective
, 2015 This is a specially commissioned editorial from the Graphene Flagship Work Package on Health and Environment. This editorial is part of the 2D Materials focus collection on 'Progress on the science and applications of two-dimensional materials ...
BIANCO, ALBERTO, PRATO, MAURIZIO
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Nanophotonics, 2020 Two-dimensional iron phosphorus trichalcogenide (FePS3) has attracted significant attention for its use in electricity, magnetism and optical fields due to its outstanding physical and chemical properties.
Xu Danyun +11 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source