Results 21 to 30 of about 123,501 (158)

Synthesis and Application of Bioactive N-Functionalized Aziridines. [PDF]

Angew Chem Int Ed Engl
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Tan H, Samanta S, Qiu N, Adibekian A, Powers DC.   +4 more
europepmc   +3 more sources

2H-Azirines as dipolarophiles [PDF]

Tetrahedron Letters, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Melo, Teresa M. V. D. Pinho e, Cardoso, Ana L., Gomes, Clara S. B., Gonsalves, António M. d'A. Rocha   +3 more
openaire   +2 more sources

Synthesis of 2-halo-2H-azirines [PDF]

Tetrahedron, 2001
Abstract α-Oxophosphonium ylides react with N -chlorosuccinimide, N -bromosuccinimide and N -iodosuccinimide in the presence of azidotrimethylsilane giving the corresponding haloazidoalkenes which were completely converted to the 2-halo-2 H -azirines on heating in heptane.
Pinho e Melo, Teresa M. V. D., Lopes, Cláudia S. J., Cardoso, Ana L., Rocha Gonsalves, António M. d'A.   +3 more
openaire   +3 more sources

Reactivity of 2-halo-2H-azirines. Part 3: Dehalogenation of 2-halo-2H-azirine-2-carboxylates [PDF]

Tetrahedron, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Pinho e Melo, Teresa M. V. D., Cardoso, Ana L., Gonsalves, António M. d'A. Rocha   +2 more
openaire   +2 more sources

Synthesis of 2-(Trifluoromethyl)Azetidines by Strain-Release Reactions of 2-(Trifluoromethyl)-1-Azabicyclo[1.1.0]Butanes. [PDF]

Chemistry
2‐(Trifluoromethyl)‐1‐azabicyclo[1.1.0]butanes, available by diastereoselective cyclopropanation of 2‐(trifluoromethyl)‐2H‐azirines, can be successfully involved in strain‐release ring‐opening processes, as illustrated by their reaction with benzyl chloroformate, trifluoroacetic anhydride or palladium‐catalyzed hydrogenolysis.
Scuiller A, Dupas A, Lefebvre G, Bouriche N, Chédotal H, Guillamot G, Cossy J, Meyer C.   +7 more
europepmc   +2 more sources

Synthetic Strategies to Access Fluorinated Azoles. [PDF]

European J Org Chem
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA, Djugovski M, Huang TY, Adhikari S, Roy S.   +4 more
europepmc   +2 more sources

Acetyl oxime/azirine 1, 3-dipole and strategy for the regioselective synthesis of polysubstituted pyrroles via [3 + 2] cycloaddition with alkyne utilizing Fe2O3@cellulose catalyst

Results in Chemistry, 2021
Fe2O3@cellulose catalyzed regioselective [3 + 2] cycloaddition of acetyl oxime with alkynes via 2H‑azirines intermediate generated in situ in an aqueous ethanolic medium is described.
Kartikey Dhar Dwivedi, Bhupender Kumar, Marri Sameer Reddy, Biplob Borah, J. Nagendra Babu, L. Raju Chowhan   +5 more
doaj   +1 more source

[3 + 2]-Cycloadditions of nitrile ylides after photoactivation of vinyl azides under flow conditions

Beilstein Journal of Organic Chemistry, 2013
The photodenitrogenation of vinyl azides to 2H-azirines by using a photoflow reactor is reported and compared with thermal formation of 2H-azirines. Photochemically, the ring of the 2H-azirines was opened to yield the nitrile ylides, which underwent a [3
Stephan Cludius-Brandt, Lukas Kupracz, Andreas Kirschning   +2 more
doaj   +1 more source

Bortrifluorid-katalysierte Umsetzung von 2H-Azirinen und Vinylaziden mit Nitrilen

CHIMIA, 1975
The reaction of 2H-azirines or vinyl azides with nitriles in the presence of boron trifluoride etherate, to yield the corresponding imidazoles (see table), is described.
Heinz Bader, Hans-Jürgen Hansen
doaj   +1 more source

Stabile Zink-Komplexe von 3-Amino-2H-azirinen

CHIMIA, 1978
3-Dimethylamino-2,2-dimethyl-2H-azirine (4a), which is known to react easily with Brönsted acids and electrophiles, forms a stable complex 5a with ZnBr2. In contrast to all other reactions of 4a, the three-membered ring in this complex is preserved. The
Kurt Dietliker, Ursula Schmid, Gabriele Mukherjee-Müller, Heinz Heimgartner   +3 more
doaj   +1 more source