Results 71 to 80 of about 136,200 (251)
Journal of Animal Reproduction and Biotechnology, 2014 The objective of this study was to determine the breed differences in the 3'-untranslated region (UTR) of MC1R mRNA, which may be used to distinguish Korean brindle cattle (Chikso) from other breeds. We investigated the relationship between the variation
Hae-Lee Lee, Jae-Hee Park, Jong Gug Kim
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Stability of mRNA/DNA and DNA/DNA duplexes affects mRNA transcription. [PDF]
PLoS ONE, 2007 Nucleic acids, due to their structural and chemical properties, can form double-stranded secondary structures that assist the transfer of genetic information and can modulate gene expression.
Rayna I Kraeva +5 more
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Functions of the 5′- and 3′-untranslated regions of tobamovirus RNA
Virus Research, 2015 The tobamovirus genome is a 5'-m(7)G-capped RNA that carries a tRNA-like structure at its 3'-terminus. The genomic RNA serves as the template for both translation and negative-strand RNA synthesis. The 5'- and 3'-untranslated regions (UTRs) of the genomic RNA contain elements that enhance translation, and the 3'-UTR also contains the elements necessary
Tetsuya, Chujo +3 more
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Pathway prediction by bioinformatic analysis of the untranslated regions of the CFTR mRNA
, 2009 Mining the information contained within the genetic code in untranslated regions has proven difficult because of the ambiguity of microRNA and protein binding sites.
Spence, Jean
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THE QUANTITATIVE IMPACT OF 3′ UNTRANSLATED REGIONS ON GENE EXPRESSION
, 2023 138 pagesRegulation of gene expression is fundamental to cell function. Post-transcriptional regulatory mechanisms, those acting directly on messenger RNA (mRNA), are increasingly appreciated for their role in shaping the transcriptome.
West, Jessica
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Advanced Science, EarlyView.Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng +14 more
wiley +1 more source
Immunity of the Saccharomyces cerevisiae SSY5 mRNA to nonsense-mediated mRNA decay.
Frontiers in Molecular Biosciences, 2014 The nonsense-mediated mRNA decay (NMD) pathway is a specialized pathway that triggers the rapid degradation of select mRNAs. Initially identified as a pathway that degrades mRNAs with premature termination codons, NMD is now recognized as a pathway that ...
Bessie Wanja Kebaara +3 more
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Genetic characterization of the coxsackievirus B2 3′ untranslated region
Journal of General Virology, 2001 The secondary structure of the 3′ untranslated region (3′UTR) of picornaviruses is thought to be important for the initiation of negative-strand RNA synthesis. In this study, genetic and biological analyses of the 3′ terminus of coxsackievirus B2 (CVB2), which differs from other enteroviruses due to the presence of five additional nucleotides prior to ...
Charlotta, Polacek, A Michael, Lindberg
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The 3′-untranslated region of the dystrophin gene – conservation and consequences of loss [PDF]
European Journal of Human Genetics, 2002 The 3'-untranslated region (3'UTR) of some vertebrate dystrophin genes shows an extraordinary degree and extent of conservation (better than that of many coding regions), a phenomenon that remains unexplained. We examine novel sequence and mutational data to explore the possible reasons for this.
Greener, M J +3 more
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m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
Advanced Science, EarlyView.This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source