Results 31 to 40 of about 18,263,514 (224)

The 1,3-dipolar cycloaddition of 1-methylphthalazinium ylides to non-symmetrically activated alkynes on a solid support under microwave irradiation [PDF]

Journal of the Serbian Chemical Society, 2006
In this paper, a comparative study of the reaction of 1-methylpihthalazinium ylides with nonsymmetrically activated alkynes in a solid media by classical heating and under microwaves is presented.
IONEL MANGALAGIU, GHEORGHITA ZBANGIOC, STEFAN DIMA   +2 more
doaj   +3 more sources

A de‐novo Approach Towards Divergent [3+2π/σ] Photocycloadditions of Nitrones via Assembly‐Controlled Kinetic Electron Transfer Gating

Angewandte Chemie, EarlyView.
A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha, Rajesh Kancherla, Jorge Escorihuela, Shana Chandran, Mrinal K. Bera, Magnus Rueping, Burkhard König   +6 more
wiley   +2 more sources

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

Angewandte Chemie, EarlyView.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy, Yoon Ho Lee, Ali Salehi Farid, Heydar Moravej, Sina Djafari Rouhani, Jennifer E. Rowley, Mohammad Rashidian, Mark D. Distefano   +7 more
wiley   +2 more sources

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process

Molecules, 2014
Diastereoselective reactions between 4-formylpyrazoles, N-substituted maleimides and glycine derivates led to new series of pyrazolyldipyrrolo [3,4-a:3',4'-f]pyrrolizines and pyrazolylpyrrolo[3,4-c]pyrroles in good yields.
Jairo Quiroga, Jaime Gálvez, Rodrigo Abonia, Braulio Insuasty, Alejandro Ortíz, Justo Cobo, Manuel Nogueras   +6 more
doaj   +1 more source

Synthesis of Thieno[2,3-d]-1,3-dithiol-2-thiones from Thieno[2,3-d]-1,2,3-thiadiazoles: Matryoshka-type autoclave for high-temperature, high-pressure thermolysis microscale reactions

Molecules, 2002
Thieno[2,3-d]-1,2,3-thiadiazoles (1) react with carbon disulfide in a "Matryoshkatype" double compartment autoclave [1] to yield thieno[2,3-d]-1,3-dithiol-2-thiones (2).
Ving J. Lee, Philip Y. Boamah, Kaberi Bhattacharya, Ulrich Jordis   +3 more
doaj   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +2 more sources

Synthesis of Different Heterocyclic Compounds of Pharmaceutical Relevance [PDF]

This thesis describes the synthesis of different cyclic imines and the exploration of their reactivity with cyclopropenones and 1,3-dipoles,as well as an investigation of the chemistry of the products.
Khan, Musharraf Naveed
core   +3 more sources

Three-Component Synthesis of Polysubstituted Homoproline Analogs

Molecules, 2005
Tetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding
V. Irkha, K. Kudryavtsev
doaj   +1 more source

Synthesis and reinvestigation of tetrazocines [PDF]

, 2004
This thesis is concerned with the study of tetrazocines. These rare, eight-membered ring systems containing four nitrogen atoms are in the infancy of their development. Little is known of their potential application, properties and generation.
Healy, Cathal
core   +2 more sources

Alkylation and 1,3-Dipolar Cycloaddition of 6-Styryl-4,5-dihydro-2H-pyridazin-3-one: Synthesis of Novel N-Substituted Pyridazinones and Triazolo[4,3-b]pyridazinones

Journal of Chemistry, 2013
Some new N-substituted pyridazinones and triazolo[4,3-b]pyridazinones were synthesized, respectively, by simple alkylation and 1,3-dipolar cycloaddition of pyridazin-3-one with nitrile imines.
Souad Mojahidi, Hanan Sekkak, El Mostapha Rakib, Maria G. P. M. S. Neves, Maria A. F. Faustino, José A. S. Cavaleiro, Hafid Zouihri   +6 more
doaj   +1 more source