Results 31 to 40 of about 25,619 (230)

Highly Enantioselective Catalytic 1,3-Dipolar Cycloaddition Involving 2,3-Allenoate Dipolarophiles [PDF]

, 2016
A bisphosphoric acid-catalyzed 1,3-dipolar cycloaddition of buta-2,3-dienoates with azomethine ylides yields 3-methylenepyrrolidine derivatives with excellent enantioselectivity (up to 97% ee)
Long He (1696168), Xiao-Hua Chen (1336080), Jin Song (276305), Jie Yu (150626), Wei-Jie Chen (288066), Liu-Zhu Gong (1499827)   +5 more
core   +3 more sources

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]

, 2014
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
O'Gorman, Paul A, Chambers, Christopher Steven, Christopher Chambers, Jamshaid, Faisal, Paul O'Gorman, Karl Hemming, Faisal Jamshaid, Hemming, Karl, Chambers, Christopher S, Christopher S. Chambers, Paul A. O'Gorman, Paul O\u27Gorman   +11 more
core   +1 more source

The 1,3-dipolar cycloaddition of 1-methylphthalazinium ylides to non-symmetrically activated alkynes on a solid support under microwave irradiation [PDF]

Journal of the Serbian Chemical Society, 2006
In this paper, a comparative study of the reaction of 1-methylpihthalazinium ylides with nonsymmetrically activated alkynes in a solid media by classical heating and under microwaves is presented.
IONEL MANGALAGIU, GHEORGHITA ZBANGIOC, STEFAN DIMA   +2 more
doaj   +3 more sources

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process

Molecules, 2014
Diastereoselective reactions between 4-formylpyrazoles, N-substituted maleimides and glycine derivates led to new series of pyrazolyldipyrrolo [3,4-a:3',4'-f]pyrrolizines and pyrazolylpyrrolo[3,4-c]pyrroles in good yields.
Jairo Quiroga, Jaime Gálvez, Rodrigo Abonia, Braulio Insuasty, Alejandro Ortíz, Justo Cobo, Manuel Nogueras   +6 more
doaj   +1 more source

Synthesis of Thieno[2,3-d]-1,3-dithiol-2-thiones from Thieno[2,3-d]-1,2,3-thiadiazoles: Matryoshka-type autoclave for high-temperature, high-pressure thermolysis microscale reactions

Molecules, 2002
Thieno[2,3-d]-1,2,3-thiadiazoles (1) react with carbon disulfide in a "Matryoshkatype" double compartment autoclave [1] to yield thieno[2,3-d]-1,3-dithiol-2-thiones (2).
Ving J. Lee, Philip Y. Boamah, Kaberi Bhattacharya, Ulrich Jordis   +3 more
doaj   +1 more source

Asymmetric isothiourea-catalysed formal [3+2] cycloadditions of ammonium enolates with oxaziridines [PDF]

, 2015
The authors thank the Royal Society for a University Research Fellowship (A.D.S.) and the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007—2013), ERC Grant Agreement No. 279850 (C.F.
McLennan, Ross, Taylor, James E., Taylor, James Edward, McLennan, Ross Sinclair, Smith, Siobhan R., Morrill, Louis Christian, Daniels, David Sydney Bernard, Smith, Siobhan Rose, Slawin, Alexandra Martha Zoya, Morrill, Louis C., Smith, Andrew D., Daniels, David S. B., Fallan, Charlene, Smith, Andrew David, Slawin, Alexandra M. Z.   +14 more
core   +1 more source

Three-Component Synthesis of Polysubstituted Homoproline Analogs

Molecules, 2005
Tetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding
V. Irkha, K. Kudryavtsev
doaj   +1 more source

Alkylation and 1,3-Dipolar Cycloaddition of 6-Styryl-4,5-dihydro-2H-pyridazin-3-one: Synthesis of Novel N-Substituted Pyridazinones and Triazolo[4,3-b]pyridazinones

Journal of Chemistry, 2013
Some new N-substituted pyridazinones and triazolo[4,3-b]pyridazinones were synthesized, respectively, by simple alkylation and 1,3-dipolar cycloaddition of pyridazin-3-one with nitrile imines.
Souad Mojahidi, Hanan Sekkak, El Mostapha Rakib, Maria G. P. M. S. Neves, Maria A. F. Faustino, José A. S. Cavaleiro, Hafid Zouihri   +6 more
doaj   +1 more source

Diethyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2,2-dicarboxylate

Acta Crystallographica Section E, 2010
The title compound, C18H22N2O7, was synthesized by the 1,3-dipolar cycloaddition reaction of but-3-en-2-one, diethyl 2-aminomalonate and 2-nitrobenzaldehyde. In the molecule, the pyrrolidine ring possesses an envelope conformation.
Long He
doaj   +1 more source

(2S)-[3-(Anthracen-9-yl)-4,5-dihydroisoxazol-5-yl]methyl 2-[(tert-butoxycarbonyl)amino]propanoate

Molbank, 2014
The synthesis of the (2S)-[3-(anthracen-9-yl)-4,5-dihydroisoxazol-5-yl]methyl 2-[(tert-butoxycarbonyl)amino]propanoate is obtained through the 1,3-dipolar cycloaddition of the stable anthracenenitrile oxide and the N-Boc protected (S)-alanine allyl ester
Misal Giuseppe Memeo, Francesco Distante, Paolo Quadrelli   +2 more
doaj   +1 more source