Results 41 to 50 of about 25,619 (230)

Asymmetric 1,3-Dipolar Cycloaddition of a (Z)-Alkene Dipolarophile. Synthesis of (3S,4R) Ethyl 1-Azabicyclo[2.2.1]heptane-3-carboxylate [PDF]

, 2016
Asymmetric 1,3-Dipolar Cycloaddition of a (Z)-Alkene Dipolarophile.
John S. Carey (2336935)
core   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes – synthesis and COX-2 inhibition activity [PDF]

, 2018
By Ru(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes 3,4-diaryl-substituted isoxazoles are formed in one step, showing high inhibition potency for COX-2.
Roscales García, Silvia, Pietzsch, Jens, Kniess, Torsten, Holger Weiss, Daniel, Torsten Kniess, Köckerling, Martin, Martin Köckerling, Bechmann, Nicole, Daniel Holger Weiss, Nicole Bechmann, Silvia Roscales, Jens Pietzsch   +11 more
core   +1 more source

Decarboxylation-Driven Double Annulations: Innovative Multi-Component Reaction Pathways

Molecules
A concerted five-component reaction strategy has been developed, featuring double [3+2] cycloadditions utilizing aspartic acid. This approach provides valuable insights into mechanistic pathways, allowing for the distinction between concerted and ...
Desheng Zhan, Gang Yang, Tieli Zhou, Sashirekha Nallapati, Xiaofeng Zhang   +4 more
doaj   +1 more source

Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues

Molecules, 2014
In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O ...
Abdelaaziz Ouahrouch, Moha Taourirte, Joachim W. Engels, Soumaya Benjelloun, Hassan B. Lazrek   +4 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

1,3-Dipolar Cycloaddition Reactions of Substituted Benzyl Azides with Acetylenic Compounds

Molecules, 2002
We review in this article some of our work which has been published over the last fifteen years in the area of 1,3-dipolar cycloaddition reactions of substituted benzyl azides with acetylenic compounds to form the corresponding 1,2-3-triazoles.
Sultan T. Abu-Orabi
doaj   +1 more source

Síntese regiosseletiva de cristais líquidos contendo o heterociclo isoxazol [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaMoléculas com características líquido-cristalinas têm ultimamente atraído um grande interesse por parte de ...
Bryk, Fernando Rebouças
core  

Ambimodal Dipolar/Diels–Alder Cycloaddition Transition States Involving Proton Transfers [PDF]

, 2018
Quantum mechanical computations and molecular dynamics simulations have been used to elucidate the factors that control reaction outcomes in ambi­modal transition states leading to both dipolar and Diels–Alder cycloaddition products, which can ...
K. N. Houk, K. N. Houk (1247004), Shuming Chen (1590061), Shuming Chen, Peiyuan Yu (1499551), Peiyuan Yu   +5 more
core   +1 more source

Highly Enantio‐ and Diastereoselective Synthesis of Tetrahydrofuran Frameworks via Chiral Lewis Acid‐Catalyzed Formal [3+2] Cycloaddition of Allylsilanes

Angewandte Chemie International Edition, EarlyView.
The first catalytic asymmetric formal [3+2] cycloaddition of allylsilanes delivers cis‐2,5‐disubstituted tetrahydrofuran‐3‐ones that serve as versatile intermediates for the synthesis of diverse bioactive scaffolds. ABSTRACT A formal [3+2] cycloaddition via cyclization/1,2‐hydride shift initiated by nucleophilic attack of allylsilanes has been ...
Hosung Lee, Dong Kyu Kim, Pingshan Xin, Jin Won Lee, Terim Seo, Do Hyun Ryu   +5 more
wiley   +1 more source