Results 71 to 80 of about 17,890 (211)

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

open access: yesChemistry – A European Journal, EarlyView.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

open access: yesMolecules, 2016
This paper describes the synthesis of precursors with a benzo[b]furan skeleton for the intramolecular 1,3-dipolar cycloaddition of azomethine ylides prepared from N-substituted 3-allyl-aminobenzo[b]furan-2-aldehydes and secondary amines derived from α ...
Martin Porubský   +2 more
doaj   +1 more source

A Tandem Chemical Vapor Deposition Platform for the Solvent‐Free Synthesis of Polypeptide Architectures

open access: yesChemistry – A European Journal, EarlyView.
A solvent‐free, two‐step chemical vapor polymerization enables efficient, substrate‐independent synthesis of surface‐attached polypeptide films. Initiator deposition via CVD is followed by NCA ring‐opening polymerization. Characterization confirms film formation and functionalization, allowing precise micropatterning and bioactive surface design for ...
Domenic Kratzer   +4 more
wiley   +1 more source

Catalytic Asymmetric Synthesis of Bicycloprolines by a 1,3-Dipolar Cycloaddition/Intramolecular Alkylation Strategy [PDF]

open access: yes, 2016
This document is the Accepted Manuscript version of a Published Work that appeared in final form inJournal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher.
Adrio, Javier   +4 more
core   +3 more sources

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Synthesis of 6-Aziridineyl and 6-Triazol-yl of D- Glucitol Derivatives [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
1,3 : 2,4 - Di - 0 -ethylidene - 5 -O - tosyl - 6 - ( 2 - cyano -1- aziridineyl ) -6- deoxy-‌D- glucitol (4) , 6- ( 2- acetate -1- aziridineyl ) derivative ( 5 ) and 6- ( 4- bromo methyl - 1,2,3- triazol -1-y1 ) ( 6 ) and the isomer ( 5- bromo methyl -1 ...
Nabil Y. J. Al-Hiti   +2 more
doaj   +1 more source

An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]

open access: yes, 2018
Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core   +1 more source

Regiospecific 1 ,3-Dipolar Cycloaddition Polymerization of Keto-Stabilized Bisalkylidenephosphoranes with Bisazides

open access: yes, 1972
Department of Chemistry, Laboratory of Macromolecular and Organic Chemistry, University of Louvain, B-3030 Heverlee, Belgium Received 4 September 1972 Thennostable poly-1,2,3-triazoles (7) were prepared by the regiospecific rt:action of bisazides with. keto-stabilhed bisalkylidenephosporanes (6) in DMSO solution.
P. YKMAN, G. L' ABBE, G. SMETS
openaire   +1 more source

Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall   +4 more
wiley   +1 more source

Syntheses and Characterizations of Some New N-alkyl, Isoxazole and Dioxazole Derivatives of 5-Chloroisatin [PDF]

open access: yes, 2017
N-alkyl and cycloadducts derivatives of 5-Chloroisatin were synthesized in good to excellent yields. The method evidences a selective N-alkylation when using 1,2-bis (2-chloroethoxy) ethane as efficient spacer at room temperature on the 5-Chloroisatin ...
Rodi, Y. K. (Y)   +3 more
core   +1 more source

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