Results 91 to 100 of about 25,619 (230)

Synthesis of oxetane/azetidine containing spirocycles via the 1,3-dipolar cycloaddition reaction [PDF]

open access: yes, 2016
Silver catalyzed 1,3-dipolar cycloaddition reactions between methyl 2-(oxetane/azetidine-3 ylidene) acetate as dipolarophiles and imines derived from –amino acid methyl esters, 2-aminomethyl pyridine and 2-aminomethyl pyrazine afforded oxetane/azetidine ...
Proud, M, Jones, B, Sridharan, V
core   +1 more source

Remarkable electronic effect on the total stereoselectivity of the cycloaddition reaction of arylnitrile oxides with pyrrol-2-one derivatives

open access: yesHeterocyclic Communications, 2019
The regiospecific 1,3-dipolar cycloaddition of 1,5-dihydropyrrol-2-one and arylnitrile oxides derivatives have been investigated. The asymmetric induction expected by the chiral centre of the 5-hydroxy-3-methyl-1,5-dihydropyrrol-2-one derivatives was ...
Guesmi A, Hamadi N Ben
doaj   +1 more source

Ultrasound-Assisted Synthesis of 1-N-glycosyl-1H-1,2,3-Triazole Derivatives and their Anti-inflammatory Activity

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
We have been synthesized various glycosyl triazoles from the reaction between glycosyl azide (1) and terminal alkynes (2a-g). The glycopiranosyl 1,2,3-triazoles (3-9) have been obtained in moderate-to-excellent yields (63-99%) through the copper (I ...
Gilson Bezerra Silva   +1 more
doaj   +1 more source

A Modular Synthesis of Isoindole/Indolizine Hybrids via the 1,3‐Dipolar Cycloaddition of Pyridine‐Based Mesoionics with Benzyne

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.
An approach to prepare pyrido[2,1‐a]isoindoles via the cycloaddition of pyridine‐based 1,3‐dipoles and benzyne is described, offering modular access to a range of substituted products by systematic tuning of the dipole. A modular strategy for the synthesis of fused indolizine/isoindole hybrids, pyrido[2,1‐α]isoindoles, via cycloaddition of pyridine ...
Samira Taghizadeh Nodehi   +2 more
wiley   +1 more source

A new chiral phosphine oxide ligand for enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides [PDF]

open access: yes, 2010
A new set of phosphorus-containing chiral ligands has been synthesized and used with silver(I) for the catalytic asymmetric 1 3-dipolar cycloaddition reaction of azomethine ylides One of these ligands (POFAM6) was found to produce an effective catalyst ...
Philip P. Garner   +5 more
core   +1 more source

Synthesis of spiro[isoindole-1,5’-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction

open access: yesBeilstein Journal of Organic Chemistry, 2016
A series of spiro[isoindole-1,5-isoxazolidin]-3(2H)-ones has been synthesized by 1,3-dipolar cycloaddition of N-benzylnitrone with isoindolin-3-methylene-1-ones.
Salvatore V. Giofrè   +10 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

Synthesis of Different Heterocyclic Compounds of Pharmaceutical Relevance [PDF]

open access: yes
This thesis describes the synthesis of different cyclic imines and the exploration of their reactivity with cyclopropenones and 1,3-dipoles,as well as an investigation of the chemistry of the products.
Khan, Musharraf Naveed
core  

First 1,3-Dipolar Cycloaddition of Azomethine Ylides With (E)-Ethyl 3-Fluoroacrylate. Regio- and Stereoselective Synthesis of Enantiopure Fluorinated Prolines. [PDF]

open access: yes, 2006
Enantiopure fluorinated prolines with four chiral centers were obtained from 1,3-dipolar cycloaddition of azomethine ylides and (E)-ethyl 3 ...
Boschi, Francesca   +15 more
core   +1 more source

Ruthenium(II)-Catalyzed Tandem C–H Allylation and [3 + 2] Dipolar Cycloaddition to Construct Bridged Tetracycles [PDF]

open access: yes
The ruthenium­(II)-catalyzed tandem C–H allylation and intramolecular dipolar cycloaddition between azomethine imines and 2-methylidenetrimethylene carbonate is described herein. The initially formed β-substituted allyl fragment could trigger the exotype
Prithwish Ghosh (7122755)   +6 more
core   +3 more sources

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