Results 91 to 100 of about 18,263,514 (224)

Die Jekyll‐und‐Hyde‐Natur von Tetrazolen in der Polymerwissenschaft: Von der intrinsischen elektronischen Dualität zur programmierbaren makromolekularen Funktion

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Ein Heterocyclus – drei elektronische Identitäten. Dieses Minireview zeigt, wie das Substitutionsmuster von Tetrazolen deren Funktion in Polymeren bestimmt und eröffnet substitutionsdefinierte Designprinzipien für funktionelle Polymermaterialien. ZUSAMMENFASSUNG Die Natur vereint Stabilität und Responsivität in einzelnen molekularen Gerüsten und ...
Meryem S. Akdemir, Hatice Mutlu
wiley   +1 more source

Asymmetric 1,3-Dipolar Cycloaddition of a (Z)-Alkene Dipolarophile. Synthesis of (3S,4R) Ethyl 1-Azabicyclo[2.2.1]heptane-3-carboxylate

, 2016
Asymmetric 1,3-Dipolar Cycloaddition of a (Z)-Alkene Dipolarophile.
John S. Carey (2336935)
core   +1 more source

Synthesis and In Silico Analysis of New Polyheterocyclic Molecules Derived from [1,4]-Benzoxazin-3-one and Their Inhibitory Effect against Pancreatic α-Amylase and Intestinal α-Glucosidase

Molecules
This study focuses on synthesizing a new series of isoxazolinyl-1,2,3-triazolyl-[1,4]-benzoxazin-3-one derivatives 5a–5o. The synthesis method involves a double 1,3-dipolar cycloaddition reaction following a “click chemistry” approach, starting from the ...
Mohamed Ellouz, Aziz Ihammi, Abdellah Baraich, Ayoub Farihi, Darifa Addichi, Saliha Loughmari, Nada Kheira Sebbar, Mohamed Bouhrim, Ramzi A. Mothana, Omar M. Noman, Bruno Eto, Fatiha Chigr, Mohammed Chigr   +12 more
doaj   +1 more source

Reaction of Nitrilimines with Pyruvaldehyde Hydrazones: Synthesis and Antimicrobial Evaluation of Some New 1,2,4-Triazole Derivatives

Journal of Chemistry, 2015
A new series of 1,3,4,5,5-pentasubstituted-1,2,4-triazoles (4a–j, 6a–j) have been synthesized by the 1,3-dipolar cycloaddition of suitable nitrilimines 2 to pyruvaldehyde (2-oxopropanal) hydrazones having (COPh, COOMe, COOEt, Me/Me, and Me/Ph) groups 3 ...
Hany M. Dalloul
doaj   +1 more source

A Novel One-Pot Green Synthesis of Dispirooxindolo-pyrrolidines via 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides

Molecules, 2015
A facile synthesis of dispirooxindolopyrrolidines has been accomplished via a one-pot three component 1,3-dipolar cycloaddition reaction. The reaction of azomethine ylides generated in situ from L-phenylalanine and substituted isatins with a series of ...
Abdulrahman I. Almansour, Natarajan Arumugam, Raju Suresh Kumar, Govindasami Periyasami, Hazem A. Ghabbour, Hoong-Kun Fun   +5 more
doaj   +1 more source

Studies on Heterocyclic Compounds. XIV. 1, 3-Dipolar Cycloaddition Reaction of Dimethyl Acetylenedicarboxylate with Phenylhydrazones

Chemical and Pharmaceutical Bulletin, 1973
1, 3-Dipolar cycloaddition of aldehyde hydrazones with dimethyl acetylenedicarboxylate without solvent gives rise to dimethyl 1, 3-diphenylpyrazole-4, 5-dicarboxylate, and in some cases trimethyl 1-phenylpyrazole-3, 4, 5-tricarboxylate as a by-product.
OGURA, HARUO, KUBO, KAZUO, WATANABE, YUMIKO, ITOH, TSUNEO   +3 more
openaire   +2 more sources

The Jekyll and Hyde Nature of Tetrazoles in Polymer Science: From Intrinsic Electronic Duality to Programmable Macromolecular Function

Angewandte Chemie International Edition, Volume 65, Issue 36, 1 September 2026.
Tetrazoles are reframed as substitution‐programmable heterocycles rather than static functional groups in polymer chemistry. By linking electronic identity to synthetic strategy and polymer architecture, this mini‐review establishes a design framework for translating tetrazole duality into predictable macromolecular function.
Meryem S. Akdemir, Hatice Mutlu
wiley   +1 more source

Synthesis of benzopyranopyrrolidines via 1,3-dipolar cycloaddition of nonstabilized azomethine ylides with 3-substituted coumarins [PDF]

, 2013
A three-component reaction of 3-substituted coumarins with N-alkyl-α-amino acids and aldehydes gave 1-benzopyrano[3,4-c]pyrrolidines as a result of a 1,3-dipolar cycloaddition of an intermediate nonstabilized azomethine ylide at the double bond of the ...
Vladimir S. Moshkin, Gerd‐Volker Roeschenthaler, Vyacheslav Ya. Sosnovskikh, Moshkin, V. S., Röschenthaler, G.-V., Sosnovskikh, V. Y.   +5 more
core   +1 more source

Convenient Synthesis and Biological Evaluation of Modafinil Derivatives: Benzhydrylsulfanyl and Benzhydrylsulfinyl [1,2,3]triazol-4-yl-methyl Esters

Molecules, 2011
Simple synthesis and biological activities of modafinil derivatives are described. The key reactions include condensation of acid and propargyl alcohol, subsequent 1,3-dipolar cycloaddition reaction of alkynes and (3-azido-propyl)cyclohexane or (4-azido ...
Seikwan Oh, Mankil Jung, Eunyoung Lim, Jee-Young Son, Yeonju Lee, Jae-Chul Jung   +5 more
doaj   +1 more source

1,3‐Dipolar Cycloaddition of Nitroalkanes as a Tool of DOS/LOS‐Like Strategy for the Synthesis of Isoxazoles and Isoxazolines

ChemistryEurope, Volume 4, Issue 9, September 2026.
A broadly applicable synthetic platform based on a DOS/LOS‐like strategy is implemented for the case of sp3‐enriched isoxazole/isoxazoline building blocks. The method is based on a [3+2] cycloaddition of nitroalkanes and various alkenes or alkynes. The utility of the proposed approach is illustrated by the discovery of JAK2‐selective inhibitors.
Bohdan A. Chalyk, Kostiantyn O. Halos, Anastasiia Grynyova, Bohdan S. Sosunovych, Bohdan V. Vashchenko, Oleksandr Zginnyk, Anna Beshtynarska, Nataliia Shliakhtova, Petro Borysko, Angelina V. Biitseva, Konstantin S. Gavrilenko, Dmytro M. Volochnyuk, Oleksandr O. Grygorenko   +12 more
wiley   +1 more source