Results 71 to 80 of about 17,972 (231)

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

open access: yesMolecules, 2016
This paper describes the synthesis of precursors with a benzo[b]furan skeleton for the intramolecular 1,3-dipolar cycloaddition of azomethine ylides prepared from N-substituted 3-allyl-aminobenzo[b]furan-2-aldehydes and secondary amines derived from α ...
Martin Porubský   +2 more
doaj   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević   +4 more
wiley   +1 more source

Ruthenium-catalyzed azide alkyne cycloaddition reaction: scope, mechanism and applications [PDF]

open access: yes, 2016
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer.
Akimova G.   +23 more
core   +2 more sources

Structure and Spectroscopy of Criegee Intermediates in Gas‐ and Aqueous Environments

open access: yesHelvetica Chimica Acta, EarlyView.
ABSTRACT The dynamics and spectroscopy of the small (H2COO) and large (CH3CHOO) Criegee intermediates (CIs) in the gas phase, inside/on water droplets, on amorphous solid water (ASW) and in bulk water are investigated using validated energy functions.
Cangtao Yin   +2 more
wiley   +1 more source

A Convenient, Safe, and Atom‐Economical Route to a Large Portfolio of Grubbs‐Type Catalysts for Olefin Metathesis via Four‐Coordinate Ruthenium Alkylidynes

open access: yesAngewandte Chemie, Volume 138, Issue 16, 13 April 2026.
It may seem counterintuitive to first target a ruthenium alkylidyne when Grubbs‐type ruthenium carbene complexes are the actual goal. In the end, however, this tactic pays valuable dividends in terms of practicality, atom economy, flexibility as well as safety: the new route provides ready access to a large assortment of catalysts for alkene metathesis
Mingxu Cui, Alois Fürstner
wiley   +2 more sources

Synthesis of 6-Aziridineyl and 6-Triazol-yl of D- Glucitol Derivatives [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
1,3 : 2,4 - Di - 0 -ethylidene - 5 -O - tosyl - 6 - ( 2 - cyano -1- aziridineyl ) -6- deoxy-‌D- glucitol (4) , 6- ( 2- acetate -1- aziridineyl ) derivative ( 5 ) and 6- ( 4- bromo methyl - 1,2,3- triazol -1-y1 ) ( 6 ) and the isomer ( 5- bromo methyl -1 ...
Nabil Y. J. Al-Hiti   +2 more
doaj   +1 more source

Regiospecific 1 ,3-Dipolar Cycloaddition Polymerization of Keto-Stabilized Bisalkylidenephosphoranes with Bisazides

open access: yes, 1972
Department of Chemistry, Laboratory of Macromolecular and Organic Chemistry, University of Louvain, B-3030 Heverlee, Belgium Received 4 September 1972 Thennostable poly-1,2,3-triazoles (7) were prepared by the regiospecific rt:action of bisazides with. keto-stabilhed bisalkylidenephosporanes (6) in DMSO solution.
P. YKMAN, G. L' ABBE, G. SMETS
openaire   +1 more source

Synthesis of enantiomeric polyhydroxyalkylpyrrolidines from 1,3-dipolar cycloadducts. Evaluation as inhibitors of a β-galactofuranosidase [PDF]

open access: yes, 2016
Enantiomeric 2,3,4-tris(hydroxyalkyl)-5-phenylpyrrolidines have been synthesized from the major cycloadducts obtained by the 1,3-dipolar cycloaddition of sugar enones with azomethine ylides derived from natural amino acids.
Oliveira Udry, Guillermo Alejandro   +3 more
core   +2 more sources

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Home - About - Disclaimer - Privacy