Results 91 to 100 of about 18,900,322 (326)

3-Hydroxybutyrate Oligomer Hydrolase and 3-Hydroxybutyrate Dehydrogenase Participate in Intracellular Polyhydroxybutyrate and Polyhydroxyvalerate Degradation in Paracoccus denitrificans [PDF]

Applied and Environmental Microbiology, 2014
ABSTRACT Genes encoding 3-hydroxybutyrate oligomer hydrolase (PhaZc) and 3-hydroxybutyrate dehydrogenase (Hbd) were isolated from Paracoccus denitrificans . PhaZc and Hbd were overproduced as His-tagged proteins in Escherichia coli and purified by affinity and gel filtration ...
Jing, Lu, Akira, Takahashi, Shunsaku, Ueda   +2 more
openaire   +2 more sources

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

¹H NMR Based Metabolomics in Human Sepsis and Healthy Serum

Metabolites, 2020
Early diagnosis is essential but challenging in severe sepsis. Quantifying and comparing metabolite concentrations in serum has been suggested as a new diagnostic tool.
Henna Jaurila, Vesa Koivukangas, Marjo Koskela, Fiia Gäddnäs, Sami Myllymaa, Arja Kullaa, Tuula Salo, Tero I. Ala-Kokko   +7 more
doaj   +1 more source

Glycerol-based additives of poly(3-hydroxybutyrate) films

, 2020
Glycerol (G), polyglycerols (PGs), glycerol triacetate (GTA), and glycerol tributyrate (GTB) were studied as additives of poly(3-hydroxybutyrate) (PHB).
Mayte M. Quispe, Olivia V. López, Dhahabia Abdallah Boina, Jean‐François Stumbé, M. Villar   +4 more
semanticscholar   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Microbial Synthesis and Characterization of Poly (3-Hydroxybutyrate-co- 4-Hydroxybutyrate) Copolymers [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2011
The research is focused on the prospective representative of the family of biodegradable polymers - polyhydroxyalkanoates (PHAs), the copolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P(3HB-co-4HB).
Natalia O. Zhila, Tatiana G. Volova, Elena D. Nikolaeva, Daria A. Syrvacheva   +3 more
doaj  

The use of sodium DL-3-Hydroxybutyrate in severe acute neuro-metabolic compromise in patients with inherited ketone body synthetic disorders

Orphanet Journal of Rare Diseases, 2020
Background Ketone bodies form a vital energy source for end organs in a variety of physiological circumstances. At different times, the heart, brain and skeletal muscle in particular can use ketones as a primary substrate.
Kaustuv Bhattacharya, Walid Matar, Adviye Ayper Tolun, Beena Devanapalli, Sue Thompson, Troy Dalkeith, Kate Lichkus, Michel Tchan   +7 more
doaj   +1 more source

Engineering Bacillus megaterium for production of functional intracellular materials [PDF]

, 2017
Background: Over the last 10-15 years, a technology has been developed to engineer bacterial polyhydroxybutyrate (PHB) inclusions as functionalized beads, for applications such as vaccines, diagnostics and enzyme immobilization. This has been achieved by
Grage, K, McDermott, P, Rehm, BHA
core   +3 more sources

Ketone Body Infusion With 3‐Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background High levels of ketone bodies are associated with improved survival as observed with regular exercise, caloric restriction, and—most recently—treatment with sodium–glucose linked transporter 2 inhibitor antidiabetic drugs.
L. Gormsen, M. Svart, H. H. Thomsen, E. Søndergaard, M. Vendelbo, N. Christensen, L. Tolbod, H. Harms, R. Nielsen, H. Wiggers, N. Jessen, Jakob Hansen, H. Bøtker, N. Møller   +13 more
semanticscholar   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source