Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco +16 more
wiley +1 more source
Solid Microneedles from Poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate): A Solvent-Free, Biodegradable Platform for Drug Delivery. [PDF]
Araújo D +3 more
europepmc +1 more source
Metabolic Stroke: Atypical Presentation of Succinic Semialdehyde Dehydrogenase Deficiency
ABSTRACT Succinic semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessive neurometabolic disorder caused by biallelic pathogenic variants in ALDH5A1, encoding the mitochondrial enzyme SSADH. This enzyme catalyses the conversion of succinic semialdehyde to succinic acid in the γ‐aminobutyric acid (GABA) degradation pathway.
Sharmila Kiss +10 more
wiley +1 more source
Improving Poly(3-Hydroxybutyrate) Properties Using Nanocellulose in Biomedical Applications: Thermal, Mechanical and Biological Studies. [PDF]
Maternia-Dudzik K +10 more
europepmc +1 more source
Mitochondrial Dysfunction in Propionic Acidemia: A Case‐Report and Review of the Literature
ABSTRACT Propionic acidemia is an inborn error of metabolism involving an enzymatic defect of propionyl‐CoA carboxylase that results in the build‐up of toxic metabolites which can induce metabolic decompensation. Secondary mitochondrial dysfunction in propionic acidemia has been commonly recognized; however, its clinical presentation and management are
Brandon K. Walther +5 more
wiley +1 more source
Poly(3-Hydroxybutyrate-Co-3-Hydroxyhexanoate): Real-Time Monitoring of Microbial Degradation via Quartz Crystal Microbalance and Electrochemical Measurement. [PDF]
Asakura N +4 more
europepmc +1 more source
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo +5 more
wiley +1 more source
Tailoring the Conductivity and Flexibility of Natural Poly(3-hydroxybutyrate-<i>co</i>-3-hydroxyvalerate)-Based Biocomposites by Introduction of Carbon Nanomaterials and Atactic Poly-3-hydroxybutyrate. [PDF]
Talaniuk V +5 more
europepmc +1 more source
Characteristics of methamphetamine‐related deaths in the United Kingdom, 1997–2024
Abstract Background and aims People who use methamphetamine have a standardised mortality ratio 6.8 times greater than the general population, with several countries reporting concerning increases in methamphetamine‐related mortality over the past decade.
Emmert Roberts +2 more
wiley +1 more source
Scalable Biosynthesis and Recovery of Poly-3-Hydroxybutyrate Produced from Cotton-Derived Glucose by <i>Cupriavidus necator</i>. [PDF]
Clark AM +4 more
europepmc +1 more source

