Results 71 to 80 of about 1,121,470 (291)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Determination of α-hydroxy acids in cosmetics by UHPLC-MS/MS

Shanghai yufang yixue
ObjectiveTo establish a UHPLC-MS/MS quantitative method for the determination of glucuronic acid， tartaric acid， glycolic acid， malic acid， lactic acid， citric acid， DL-2-hydroxybutyric acid sodium， mandelic acid， benzilic acid， hydroxycaprylic acid ...
RU Ge, XU Yong, HAN Jing, ZHANG Kai, PENG Xingsheng, ZHENG Rong   +5 more
doaj   +1 more source

Efficient production and secretion of oxaloacetate from Halomonas sp. KM-1 under aerobic conditions

AMB Express, 2017
The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize glucose for the intracellular storage of the bioplastic poly-(R)-3-hydroxybutyric acid (PHB) and extracellular secretion of pyruvate under aerobic conditions.
Asuka Hannya, Taku Nishimura, Isao Matsushita, Jun Tsubota, Yoshikazu Kawata   +4 more
doaj   +1 more source

Effects of different sodium salts and nitrogen sources on the production of 3-hydroxybutyrate and polyhydroxybutyrate by Burkholderia cepacia

Bioresources and Bioprocessing, 2021
The effects of NaCl, Na2SO4, Na2HPO4, and Na3C6H5O7 on the production of 3-hydroxybutyrate, polyhydroxybutyrate, and by-products by Burkholderia cepacia.
Jianfei Wang, Jiaqi Huang, Huanyu Guo, Shaoming Jiang, Jinyue Qiao, Xingyu Chen, Zixuan Qu, Wanyue Cui, Shijie Liu   +8 more
doaj   +1 more source

Treating substance abuse is not enough: Comorbidities in consecutively admitted female prisoners [PDF]

, 2015
Publisher Copyright: © 2015 Elsevier Ltd.Introduction: Several studies have pointed to high rates of substance use disorders among female prisoners. The present study aimed to assess comorbidities of substance use disorders with other mental disorders in
Adrian P. Mundt, Andreas Ströhle, Arntz, Binswanger, Brooke, Burling, Butler, Clarke, Compton, Daniel, Driessen, Dudeck, Fazel, Fazel, Fazel, First, Fydrich, Goldner, Gunter, Heatherton, Jacobi, Jan Mir, Johnson, Jordan, Maden, Mundt, Mundt, Norbert Konrad, Payne, Priebe, Schenk, Sheehan, Sheehan, Sinja Kastner, Steadman, Stefan Priebe, UNESCO Institute for Statistics, van den Bergh, van Emmerik-van Oortmerssen, von Schönfeld, Walmsley, Wright   +41 more
core   +1 more source

Microbial influences on immune modulation and colorectal cancer progression through combined transcriptomic and microbiomic analysis

iMetaOmics, EarlyView.
Schematic representation of the distinct tumor microenvironment characteristics in CA1 and CA2 subtypes. CA1 illustrates an immune‐active tumor microenvironment characterized by elevated infiltration of immune cells, particularly CD8 + T cells and macrophages, and enhanced IFN‐γ signaling.
Shuting Xia, Likun Wang, Yangzhuo Xu, Jiaqi Zhang, Zeyang Zhou, Libing Sun, Heng Li, Chungen Xing, Jialu Mao, Yina Liu, Fulin Yang, Ling Zhong, Jiancheng Xu, Xiaodong Yang, Zhemin Zhou   +14 more
wiley   +1 more source

Association of circulating metabolites and polygenic risk score with incident type 2 diabetes: a prospective community-based cohort study

Cardiovascular Diabetology
Background No previous studies have explored metabolites associated with both genetic predispositions to type 2 diabetes (T2DM) and T2DM onset. Therefore, we aimed to explore metabolic profiles using genetic risk to identify pathways for tailored T2DM ...
Masato Takase, Naoki Nakaya, Mana Kogure, Rieko Hatanaka, Kumi Nakaya, Ippei Chiba, Sayuri Tokioka, Kotaro Nochioka, Tomohiro Nakamura, Naho Tsuchiya, Takumi Hirata, Seizo Koshiba, Kazuki Kumada, Ikuko Motoike, Eiji Hishinuma, Akira Narita, Taku Obara, Mami Ishikuro, Hisashi Ohseto, Ippei Takahashi, Tomoko Kobayashi, Eiichi N. Kodama, Yohei Hamanaka, Masatsugu Orui, Soichi Ogishima, Satoshi Nagaie, Nobuo Fuse, Junichi Sugawara, Shinichi Kuriyama, Koichi Matsuda, Yoko Izumi, Kinuko Ohneda, Kengo Kinoshita, Atsushi Hozawa, Masayuki Yamamoto, Biobank Japan Project, the ToMMo investigators   +36 more
doaj   +1 more source

Ribose and related sugars from ultraviolet irradiation of interstellar ice analogues [PDF]

, 2016
International audienceThis folder includes:*Supplementary Material (.pdf)(Materials and Methods, Figs. S1–S6, Table S1, caption for movie S1)Other supplementary materials available for this manuscript: *Movie S1 (.mp4)*GC×GC chromatograms of ice sample ...
Buhse, Thomas, de Marcellus, Pierre, Hoffmann, Søren V., Le Sergeant D’hendecourt, Louis, Meierhenrich, Uwe J., Meinert, Cornelia, Myrgorodska, Iuliia, Nahon, Laurent   +7 more
core   +4 more sources

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Production of Two- and Three-Component Polyhydroxyalkanoates by Luminous Bacteria of the Photobacterium Genus [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2016
The study addresses the ability of luminous bacteria Photobacterium leiognathi Boisvert et al. and Photobacterium phosphoreum (Cohn) Beijerinck to synthesize polyesters of hydroxycarbon acids (polyhydroxyalkanoates, PHAs) as storage macromolecules.
Anatoly N. Boyandin
doaj