Results 81 to 90 of about 1,374,074 (257)

Phase diagrams in blends of poly(3-hydroxybutyric acid) with various aliphatic polyesters

open access: yeseXPRESS Polymer Letters, 2011
Phase behavior with immiscibility, miscibility, crystalline morphology, and kinetic analysis in blends of poly(3-hydroxybutyric acid) (PHB) with aliphatic polyesters such as poly(butylene adipate) (PBA), poly(ethylene adipate) (PEA), poly(trimethylene ...
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

A histochemical study on hydrolytic and oxidative enzymes in human sarcomas [PDF]

open access: yes, 1966
Histochemical evaluations of human sarcomas such as reticulum cell sarcoma, fibrosarcoma, lymphosarcoma and neurofibrosarcoma, were carried out with five hydrolytic enzymes and eight oxidative enzymes.
Kawashima, Takao   +6 more
core   +1 more source

Solvent‐Dependent Biological Activities of Aqueous and Ethanolic Extracts From Edible Insect Larvae

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This study compares the functional activity profiles of aqueous and ethanolic extracts from edible insect larvae. Solvent‐dependent extraction resulted in distinct bioactivity patterns, highlighting the importance of extraction conditions in determining the functional potential of insect‐derived bioactive compounds.
Min‐Cheol Kang   +9 more
wiley   +1 more source

Metabolic profiles of saliva in male mouse models of chronic sleep disorders induced by psychophysiological stress

open access: yesScientific Reports, 2023
Disordered sleep is a global social problem and an established significant risk factor for psychological and metabolic diseases. We profiled non-targeted metabolites in saliva from mouse models of chronic sleep disorder (CSD).
Katsutaka Oishi   +6 more
doaj   +1 more source

The synthesis and structural characterization of graft copolymers composed of γ-PGA backbone and oligoesters pendant chains [PDF]

open access: yes, 2017
© 2017 The Authors. Published by American Chemical Society. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1021/jasms ...
Adamus, Grażyna   +5 more
core   +2 more sources

Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age‐Associated Gut–Brain Axis Profiles

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni   +16 more
wiley   +1 more source

γ-Aminobutyric AcidB(GABAB)-Receptor Mediation of Different In Vivo Effects of γ-Butyrolactone

open access: yesJournal of Pharmacological Sciences, 2008
The endogenous brain constituent, γ-hydroxybutyric acid (GHB), as well as its prodrug, γ-butyrolactone (GBL), have recently gained interest in the drug addiction field due to their abuse potential and fatalities caused by overdose.
Mauro A.M. Carai   +5 more
doaj   +1 more source

Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites [PDF]

open access: yes, 2016
Epidemiological research has demonstrated that the consumption of red meat is an important risk factor for the development of colorectal cancer (CRC), diabetes mellitus and cardiovascular diseases.
De Smet, S.   +5 more
core   +2 more sources

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2219-2235, May 2026.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

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