Results 41 to 50 of about 2,128 (126)
Histologic Response to Induction Chemotherapy in High‐Risk Neuroblastoma
ABSTRACT Introduction Tumor histology at diagnosis is used in conjunction with other prognostic features to risk stratify patients with neuroblastoma and to assign therapy regimens. In patients with high‐risk disease, adjustment of therapy is tailored to treatment response, largely based on disease imaging following induction chemotherapy and resection
Monica Pomaville +4 more
wiley +1 more source
ABSTRACT Objectives The primary objective was to assess the accuracy of prenatal examination in detecting and characterizing perinatal solid tumors of the thoracoabdominopelvic region. Secondary objectives were to describe the epidemiology, clinical characteristics and outcome of these tumors.
C. Khawand +23 more
wiley +1 more source
Abstract Dementia with Lewy bodies (DLB), a progressive neurodegenerative disease with heterogeneous clinical presentations, greatly impacts patients, caregivers, and society. Despite its frequency, diagnosing and treating DLB remains challenging. Advances in in vivo biomarker assays reflecting underlying pathology are improving disease identification,
Jennifer G. Goldman +19 more
wiley +1 more source
파킨슨병과 다계통 위축증 환자들에서 후각기능 및 후각기능과 심장 123I-MIBG섭취율과의 연관성 [PDF]
Background: Tetanus toxin selectively blocks inhibitory synapses in the brainstem as well as the spinal cord. Therefore, in contradiction to Stiff Person syndrome, patients with generalized tetanus usually show abnormal masseter silent periods as well as
김, 현준 +3 more
core
Naïve Bayes Alpha Parameter Optimization with Ant Colony for Clinical Text Classification [PDF]
This study addresses the challenges of text classification in domain-specific Natural Language Processing (NLP) within the medical field, which differs significantly from general NLP due to the presence of complex medical jargon and informal language in ...
Dafwen Toresa +4 more
core +2 more sources
Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
Progranulin Mutation Manifesting as Parkinson Disease: A Case Series from the PADUA‐CESNE Cohort
Abstract Background Mutations in progranulin (GRN) are associated with frontotemporal dementia, although a Parkinson disease (PD) phenotype is uncommon, especially in young patients. Cases We report three subjects from the PADUA‐CESNE cohort, meeting diagnostic criteria for PD, with onset under age 55.
Giulia Bonato +8 more
wiley +1 more source
Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine
Abstract Cancer molecular imaging is the noninvasive visualization of a process unique to or altered in neoplasia, such as proliferation, glucose metabolism, and receptor expression, which is relevant to patient management. Several molecular imaging modalities are now available, including magnetic resonance, optical, and nuclear imaging.
Malik E. Juweid +6 more
wiley +1 more source
心疾患におけるMIBG 心筋シンチグラフィの有用性と定量解析における注意点 [PDF]
123I-MIBG(3-iodobenzylguanidine)は心臓交感神経機能を客観的に評価できる検 査法で,心不全症例の重症度評価,予後予測,治療効果の評価などに多くの有用な 情報を提供する。正面プラナー像における心臓/縦隔比(H/M 比)と洗い出し率 (washout rate)が定量指標として汎用されているが,施設間較差の存在が大きな問 題となっている。MIBG は負荷心筋血流SPECT と比較するとエビデンスが不十分 であり,今後は定量値算出法の標準化を図り,多施設共同研究が可能な環境を実現
山科 昌平
core +1 more source

