Results 21 to 30 of about 2,128 (126)

I-131 Metaiodobenzylguanidine Therapy of Neuroectodermal Tumors [PDF]

open access: yes, 2017
I-131 metaiodobenzylguanidine (MIBG) is a noradrenaline analogue and acts as an adrenergic neuron blocker. It is commonly used in the radionuclide treatment of neuroectodermal-derived tumors (Stage III–IV neuroblastoma, inoperable pheochromocytoma ...
Araz, Mine, Çayır, Derya
core   +2 more sources

Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195

open access: yesEJNMMI Research, 2018
Background 18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine (18F-LMI1195) is a new class of PET tracer designed for sympathetic nervous imaging of the heart.
Xinyu Chen   +7 more
doaj   +1 more source

Initial Evaluation of AF78: a Rationally Designed Fluorine-18-Labelled PET Radiotracer Targeting Norepinephrine Transporter [PDF]

open access: yes, 2019
Purpose Taking full advantage of positron emission tomography (PET) technology, fluorine-18-labelled radiotracers targeting norepinephrine transporter (NET) have potential applications in the diagnosis and assessment of cardiac sympathetic nerve ...
Chen, Xinyu   +9 more
core   +1 more source

RADIOIODINATED COMPOUNDS [PDF]

open access: yes, 2018
This disclosure relates to reagents and methods useful in the synthesis of aryl iodines ,for example , in the preparation of iodine labeled radiotracers .
DiMagno, Stephen, Hu, Bao
core   +3 more sources

Cardiac 123I-MIBG uptake in de novo Brazilian patients with Parkinson's disease without clinically defined dysautonomia [PDF]

open access: yes, 2014
Myocardial scintigraphy with meta-iodo-benzyl-guanidine (123I cMIBG) has been studied in Parkinson's disease (PD), especially in Asian countries, but not in Latin America.
Adriana S. X. de Brito   +34 more
core   +2 more sources

Rational Synthesis and Application of Aryl Iodides in Electrochemical Reactions and Theoretical Studies on the CBS Catalyst [PDF]

open access: yes, 2018
Within this dissertation three different projects are discussed. The underlying theme of all projects is the application of computational and/or statistical methods in order to decrease the experimental effort and to increase the information output at ...
Möckel, Robert
core   +1 more source

Nuclear Medicine Imaging in Neuroblastoma: Current Status and New Developments [PDF]

open access: yes, 2021
Neuroblastoma is the most common extracranial solid malignancy in children. At diagnosis, approximately 50% of patients present with metastatic disease.
Bleeker, Gitta   +9 more
core  

Cardiac MIBG Scintigraphy in Neurodegenerative Parkinsonism: Limitations in Clinical Practice

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Reduced cardiac uptake on 123Iodine‐metaiodobenzylguanidine (MIBG) scintigraphy is a valuable tool for differentiating neurodegenerative parkinsonism but interpretation can be difficult due to comorbidities and drug‐tracer interactions.
Frank Jagusch   +9 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

open access: yesPediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij   +11 more
wiley   +1 more source

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