Results 71 to 80 of about 3,761 (182)

Structural and functional characterization of sulfurtransferase from Frondihabitans sp. PAMC28461.

open access: yesPLoS ONE
Sulfurtransferases transfer of sulfur atoms from thiols to acceptors like cyanide. They are categorized as thiosulfate sulfurtransferases (TSTs) and 3-mercaptopyruvate sulfurtransferases (MSTs). TSTs transfer sulfur from thiosulfate to cyanide, producing
Hackwon Do   +9 more
doaj   +1 more source

Sequential Accumulation of ‘Driver’ Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids

open access: yesAntioxidants, 2022
Recently, a CRISPR-Cas9 genome-editing system was developed with introduced sequential ‘driver’ mutations in the WNT, MAPK, TGF-β, TP53 and PI3K pathways into organoids derived from normal human intestinal epithelial cells.
Kelly Ascenção   +5 more
doaj   +1 more source

Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons. [PDF]

open access: yes, 2019
Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood.
Bartlett, Douglas H   +24 more
core   +2 more sources

3-Mercaptopyruvate sulfurtransferase disruption in dermal fibroblasts facilitates adipogenic trans-differentiation

open access: yesExperimental Cell Research, 2019
Transitioning from a differentiated state to a higher-order of plasticity, by partial rather than full reactivation of pluripotency genes, might be a better approach in regenerative medicine. Hydrogen sulfide plays a crucial role in the maintenance and differentiation of mesenchymal stem cells (MSC) that have the potential to differentiate to a diverse
Elena A, Ostrakhovitch   +3 more
openaire   +2 more sources

Sulfur Administration in Fe–S Cluster Homeostasis

open access: yesAntioxidants, 2021
Mitochondria are the key organelles of Fe–S cluster synthesis. They contain the enzyme cysteine desulfurase, a scaffold protein, iron and electron donors, and specific chaperons all required for the formation of Fe–S clusters.
Leszek Rydz   +2 more
doaj   +1 more source

Metabolism of 3-mercaptopyruvate in rat tissues. [PDF]

open access: yes, 1983
Metabolism of 3-mercaptopyruvate was investigated using homogenates of rat heart, liver and kidney. When 3-mercaptopyruvate was incubated with heart homogenate, L-cysteine, L-alanine, S-(2-hydroxy-2-carboxyethylthio)-L-cysteine and 3-mercaptolactate were
Kiguchi, Shozo
core   +1 more source

Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system. [PDF]

open access: yes, 2017
There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two ...
Bucci, M., Cirino, G, Vellecco, V
core   +1 more source

Dimethyl Sulfoxide (DMSO) as a Potential Source of Interference in Research Related to Sulfur Metabolism—A Preliminary Study

open access: yesAntioxidants
Dimethyl sulfoxide (DMSO), an organosulfur compound, is widely used as the gold standard solvent in biological research. It is used in cell culture experiments and as a component of formulations in in vivo studies.
Marta Kaczor-Kamińska   +5 more
doaj   +1 more source

Thiosulfate-cyanide sulfurtransferase a mitochondrial essential enzyme: from cell metabolism to the biotechnological applications [PDF]

open access: yes, 2022
Thiosulfate: cyanide sulfurtransferase (TST), also named rhodanese, is an enzyme widely distributed in both prokaryotes and eukaryotes, where it plays a relevant role in mitochondrial function. TST enzyme is involved in several biochemical processes such
Arciero I., Buonvino S., Melino S.
core   +1 more source

Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes [PDF]

open access: yes, 2015
Our investigation showed that hepatocytes isolated from cysteine dioxygenase knockout mice (Cdo1(−/−)) had lower levels of hypotaurine and taurine than Cdo1(+/+) hepatocytes. Interestingly, hypotaurine accumulates in cultured wild-type hepatocytes.
Halina Jurkowska   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy