Results 61 to 70 of about 5,846 (172)

ATF2 promotes urothelial cancer outgrowth via cooperation with androgen receptor signaling

Endocrine Connections, 2018
We investigated the functional role of ATF2, a transcription factor normally activated via its phosphorylation in response to phospho-ERK/MAPK signals, in the outgrowth of urothelial cancer.
Satoshi Inoue, Taichi Mizushima, Hiroki Ide, Guiyang Jiang, Takuro Goto, Yujiro Nagata, George J Netto, Hiroshi Miyamoto   +7 more
doaj   +1 more source

Observations on Effect of 3-Methylcholanthrene in Scorbutic Guinea Pigs

Experimental Biology and Medicine, 1961
Summary1. Some of the pathoses of scurvy in guinea pigs were reversed by administration of 3-methylcholanthrene. These included a marked reduction of incidence of hemorrhage, reduction of bone resorption, preservation of dentinogenesis and prevention of death of odontoblasts. 2.
G R, MARTIN, H M, FULLMER, J J, BURNS
openaire   +2 more sources

Inhibitory Effects of 3-Methylcholanthrene Exposure on Porcine Oocyte Maturation. [PDF]

Int J Mol Sci, 2023
Zhang M, Wang X, Liu Q, Yan Y, Xu C, Zhu Z, Wu S, Zuo X, Zong Y, Li C, Zhang Y, Cao Z.   +11 more
europepmc   +1 more source

Role of Latrophilin‐1 and Latrophilin‐2 as Downstream Effectors of Androgen Receptor Signaling in Urothelial Tumorigenesis

Cancer Reports
Background Accumulating evidence indicates a critical role of androgen receptor (AR) in the pathogenesis of male‐dominant urothelial cancer. Meanwhile, the functions of latrophilins (LPHNs), a subfamily of G protein‐coupled receptors, remain largely ...
Takuro Goto, Yuki Teramoto, Mohammad Amin Elahi Najafi, Masato Yasui, Gaku Yamamichi, Takuo Matsukawa, Hiroshi Miyamoto   +6 more
doaj   +1 more source

Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice. [PDF]

Methods Cell Biol, 2021
Bauer AK, Dwyer-Nield LD.
europepmc   +1 more source

Novel insights into SNORD-78 and miR-122-5P the predicted diagnostic indexes of lung cancer: drug-loaded liposome formulations competing methylcholanthrene-induced lung cancer

Cancer Nanotechnology
Micro-RNAs (mi-RNAs) can regulate various tumor suppressor genes or oncogenes thus they were monitored in various types of cell carcinoma. Lung cancer extensive progress has led not only to understanding the molecular pathways governing human lung cancer,
Mai O. Kadry, Rehab M. Abdel-Megeed
doaj   +1 more source

Identification and editing of stem-like cells in methylcholanthrene-induced sarcomas

OncoImmunology, 2019
The cancer stem cell (CSC) paradigm posits that specific cells within a tumor, so-called CSC-like cells, have differing levels of tumorigenicity and chemoresistance.
Emilie T. E. Gross, Carlos D. Peinado, Yujin Jung, Semi Han, Beichen Liu, Endi K. Santosa, Jack D. Bui   +6 more
doaj   +1 more source

Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

Journal of Experimental & Clinical Cancer Research, 2018
Background The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution of Tspan8 and CD151 to host versus tumor-derived exosome (TEX) activities being not ...
Kun Zhao, Zhe Wang, Thilo Hackert, Claudia Pitzer, Margot Zöller   +4 more
doaj   +1 more source

Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel.

PLoS ONE, 2018
In 2017, the International Agency for Research on Cancer classified welding fumes as "carcinogenic to humans" (Group 1). Both mild steel (MS) welding, where fumes lack carcinogenic chromium and nickel, and stainless steel (SS) increase lung cancer risk ...
Lauryn M Falcone, Aaron Erdely, Rebecca Salmen, Michael Keane, Lori Battelli, Vamsi Kodali, Lauren Bowers, Aleksandr B Stefaniak, Michael L Kashon, James M Antonini, Patti C Zeidler-Erdely   +10 more
doaj   +1 more source

Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner

Particle and Fibre Toxicology, 2010
Background Elevated levels of air pollution are associated with increased risk of lung cancer. Particulate matter (PM) contains transition metals that may potentiate neoplastic development through the induction of oxidative stress and inflammation, a ...
Bauer Alison K, Walters Dianne M, Rondini Elizabeth A   +2 more
doaj   +1 more source