Results 51 to 60 of about 13,770,514 (290)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The complexity of class OTHER-NP
, 2018 P versus NP is considered as one of the most important open problems in computer science. This consists in knowing the answer of the following question: Is P equal to NP?
Frank Vega (4690180)
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecules, 2018 Nanostructured β-CoMoO4 catalysts have been prepared via the thermal decomposition of an oxalate precursor. The catalyst was characterized by infrared spectroscopy (FTIR), X-ray diffraction (XRD), Brunauer-Emmett-Teller method (BET), energy dispersive X ...
Fahd Al-Wadaani +6 more
doaj +1 more source
Neuroprotective effect of Zingiber officinale in 3-np-induced huntington disease
IOSR Journal of Pharmacy (IOSRPHR), 2012 –Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disease that causes clinical manifestations such as progressive choreiformic movements, cognitive abnormality and psychiatric deterioration. HD results from the destruction of neurons in the basal ganglia, and oxidative stress, Exitotoxicity and energy impairment hasbeen ...
openaire +1 more source
, 2023 462.A.5.3(2).pdf created from original election material in the South African Elections Collection held in the Manuscripts Section of the Stellenbosch Library and Information Service.Sticker as marketing material for the National Party (NP) featuring an ...
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The complexity of class TAUTOLOGY-NP
, 2018 P versus NP is considered as one of the most important open problems in computer science. This consists in knowing the answer of the following question: Is P equal to NP?
Frank Vega (4690180)
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source