Results 61 to 70 of about 19,351,043 (289)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Altered stimulus frequency and intensity dependence of the somatosensory evoked potential in rats after acute application of two mitochondrial toxins [PDF]
, 2009 Mitochondrial toxins are a special group of toxicants with nervous system ef TRACT - fects. The resulting nervous system damage could be detected and followed-up by means of functional biomarkers but these still have to be worked out.
Bankó, S., Papp, András, Takács, Sz.
core +1 more source
Two Species Evolutionary Game Model of User and Moderator Dynamics
, 2012 We construct a two species evolutionary game model of an online society consisting of ordinary users and behavior enforcers (moderators). Among themselves, moderators play a coordination game choosing between being "positive" or "negative" (or harsh ...
Fan, James +3 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The FASEB Journal, 2009 The 3‐nitropropionic acid model Of Huntington's disease produces a variety of biochemical anomalies. One of these, is the activation of the protease calpain. Excess calpain activity is probably responsible for major cell death expressed as striatial degeneration.
Leo Kesner +5 more
openaire +1 more source
Effects of 3-nitrpropionic acid in rats: general toxicity and neurotoxicity [PDF]
, 2005 Three-nitropropionic acid (3-NP) causes biochemical and morphological alterations in human and animal brain. Young adult male Wistar rats received 3-NP ip. on 5 consecutive days and were investigated four weeks later (subacute treatment).
Nagymajtényi, László +2 more
core
Regularized zero-range model and an application to the triton and the hypertriton [PDF]
, 2001 We examine the regularized zero-range model in an application to three-fermion systems -- the triton and the hypertriton. We consider bound states and low-energy neutron-deuteron and lambda-deuteron scattering.
A.S. Jensen +27 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
NanomaterialsThe utilization of a nanoporous (NP) GaN fabricated by electrochemical etching has been demonstrated to be effective in the fabrication of a high-performance ultraviolet (UV) photodetector (PD).
Junjie Wen +6 more
doaj +1 more source
, 2012 The earlier-developed ab initio model and the kinetic Monte Carlo method (KMCM) are used to simulate precipitation in a number of iron-copper alloys with different copper concentrations x and temperatures T.
A V Barashev +23 more
core +1 more source