Results 31 to 40 of about 10,175,510 (387)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Too Undisciplined to Legislate? Party Unity and Policy-making in Brazil Demasiado indisciplinados para gobernar? Unidad partidaria y elaboración de políticas en Brasil

Journal of Politics in Latin America, 2012
Discipline and cohesiveness of political parties are essential for legislatures to engage in policy-making. Parties in Brazil have historically been considered ideologically weak and uninvolved in policy issues of national importance.
Sylvia Gaylord
doaj  

A new luminous supersoft X-ray source in NGC 300 [PDF]

, 2006
Context. We report the discovery of a new luminous supersoft source, XMMU J005455.0−374117, in the nearby spiral galaxy GC 300, in XMM-Newton observations performed on 2005 May 22 and on 2005 November 25.
Benlloch, Carpano, Di Stefano, Di Stefano, Dickey, E. Kendziorra, Fabbiano, Gieren, Greiner, J. Wilms, King, Kong, Kong, Lomb, Long, M. Schirmer, Mukai, Mukai, Narayan, Nowak, Orio, Read, Read, S. Carpano, Schirmer, Strüder, Swartz, Turner, van den Heuvel, Watarai   +29 more
core   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Attitudes, Ideological Associations and the Left–Right Divide in Latin America Actitudes, Asociaciones Ideológicas y la Dimensión de Izquierda-Derecha en América Latina

Journal of Politics in Latin America, 2012
Do Latin American citizens share a common conception of the ideological left–right distinction? And if so, is this conception linked to individuals’ ideological self-placement?
Nina Wiesehomeier, David Doyle
doaj  

HAMPARAN JACQUES DERRIDA: TEORI POSTMODERNISME DALAM WACANA DALAM WACANA SENI PERTUNJUKAN [PDF]

, 2004
Kanizar1 Abstract: Deconstruction is a strike of postmodernism to the modern thought that is always subjectively functional, structural, and paradigmatic. Postmodernism deconstructs functional thought that maintain stability, deconstructs structuralism
Ka, nizar
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Oligarchy in Thailand?

Journal of Current Southeast Asian Affairs, 2015
A modern conception of oligarchy, which can be housed under an authoritarian regime as easily as it can under a liberal democratic one, can affect our understanding of the potential national political repercussions of extreme inequalities of wealth. This
T. F. Rhoden
doaj  

Real‐world evidence concerning clinical and economic outcomes of switching to insulin glargine 300 units/mL vs other basal insulins in patients with type 2 diabetes using basal insulin

Diabetes, obesity and metabolism, 2018
This retrospective cohort study compared real‐world clinical and healthcare‐resource utilization (HCRU) data in patients with type 2 diabetes using basal insulin (BI) who switched to insulin glargine 300 units/mL (Gla‐300) or another BI.
F. Zhou, F. Ye, P. Berhanu, Vineet E Gupta, Rishab A Gupta, J. Sung, J. Westerbacka, T. Bailey, L. Blonde   +8 more
semanticscholar   +1 more source

Arc Phenomena in low-voltage current limiting circuit breakers [PDF]

, 2010
Circuit breakers are an important safety feature in most electrical circuits, and they act to prevent excessive currents caused by short circuits, for example. Low-voltage current limiting circuit breakers are activated by a trip solenoid when a critical
Budd, Chris, Dellar, Paul, McGuinness, M., Richardson, G., Thompson, Alice B.   +4 more
core