Results 31 to 40 of about 2,232,606 (299)
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
The Crux Is the Skin: Reflections on Southeast Asian Personhood
This essay is an exercise in the phenomenology of personhood based on some 25 years of field research among Javanese, Thai, and Filipinos. As I still slip up from time to time, I am convinced that it is relevant to both scholarly researchers and others ...
Niels Mulder
doaj
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Book Review: Haberkorn, Tyrell, Revolution Interrupted: ...
Book Review of the monograph: Haberkorn, Tyrell (2011), Revolution Interrupted: Farmers, Students, Law and Violence in Northern Thailand Madison, Wisconsin: University of Wisconsin Press, ISBN: 978 0 299 28184 7, 256 ...
Fabian Drahmoune
doaj
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Low-Level Corruption Tolerance: An “Action-Based†Approach for Peru and Latin America
Since the beginning of the past decade, the tolerance of corruption by citizens of most Latin American countries has become a concept in its own right within the broader study of corruption. This construct, however, lacks a systematic approach and is yet
Joseph Pozsgai Alvarez
doaj
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
The Role of Religion and Ethnicity in Jakarta’s 2012 Gubernatorial Election
The victory of Joko Widodo (‘Jokowi’) in Jakarta’s 2012 gubernatorial election has been described as a “triumph of democracy†as Joko and his running mate Basuki Tjahaja Purnama (‘Ahok’), a Chinese Christian, successfully won the election ...
Ken Miichi
doaj
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source