Results 31 to 40 of about 8,871,631 (366)
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
Peer assessment and feedback : opportunities for implementation in dietetic practice education [PDF]
, 2010 This paper explores the role of peer or collaborative learning, and the implementation of peer assessment, a part of dietetic practice education, which is an integral part of all student dietitians' academic ...
Kershaw, Ruth
core
Clinical features of a novel TIMP-3 mutation causing Sorsby's fundus dystrophy: implications for disease mechanism [PDF]
, 2001 AIMS: To describe the phenotype in three family members affected by a novel mutation in the gene coding for the enzyme tissue inhibitor of metalloproteinase-3 (TIMP-3). METHODS: Three members of the same family were seen with a history of nyctalopia and
Barker, M.D. +6 more
core +2 more sources
Journal of Current Southeast Asian Affairs, 2016 In political science and in development cooperation, civic organisations (COs) under authoritarian rule are usually seen as supporters of processes that move towards democratisation. However, these organisations are sometimes criticised for their support
Jörg Wischermann +2 more
doaj
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Africa Spectrum, 2010 In this farewell lecture on the occasion of his departure as Professor of Development in sub-Saharan Africa at Leiden University and Director of the African Studies Centre (ASC), Leiden, the author starts with the vuvuzela issue as an illustration of the
Leo J. de Haan
doaj
The Episodic, Precessing Giant Molecular Outflow from IRAS 04239+2436 (HH 300) [PDF]
, 2001 We present the first set of detailed molecular line maps of the region associated with the giant Herbig-Haro flow HH 300, from the young star IRAS 04239+2436. Our results indicate that the red lobe of the HH 300 flow is depositing a fair amount of momentum and kinetic energy over a notable volume of its host dark cloud.
arxiv +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Building distributed heterogeneous smart phone Java applications an evaluation from a development perspective [PDF]
, 2009 The advances in mobile phone technology have enabled such devices to be programmed to run general-purpose applications using a special edition of the Java programming language.
Abdul Salam, Rosalina +3 more
core
Betwixt Droughts and Floods: Flood Management Politics in Thailand
Journal of Current Southeast Asian Affairs, 2015 Attempting to create greater understanding of the political dynamics that influence domestic disaster relief and management (DRM) in Thailand, this article takes a closer look at these dynamics by outlining the main actors involved in flood-related DRM ...
Naila Maier-Knapp
doaj