Results 31 to 40 of about 3,137,133 (371)

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1992
A bacterial cloning system for mapping and analysis of complex genomes has been developed. The BAC system (for bacterial artificial chromosome) is based on Escherichia coli and its single-copy plasmid F factor.
H. Shizuya   +6 more
semanticscholar   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Book Review: Jandl, Thomas, Vietnam in the Global Economy – The Dy-namics of Integration, Decentralization and Contested Politics

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the Monograph: Thomas Jandl (2013), Vietnam in the Global Economy – The Dynamics of Integration, Decentralization and Contested Politics.
Adam Fforde
doaj  

Hectospec, the MMT's 300 Optical Fiber-Fed Spectrograph [PDF]

open access: yesPubl.Astron.Soc.Pac.117:1411-1434,2005, 2005
The Hectospec is a 300 optical fiber fed spectrograph commissioned at the MMT in the spring of 2004. A pair of high-speed six-axis robots move the 300 fiber buttons between observing configurations within ~300 s and to an accuracy ~25 microns. The optical fibers run for 26 m between the MMT's focal surface and the bench spectrograph operating at R~1000-
arxiv   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Measuring Institutional Trust: Evidence from Guyana

open access: yesJournal of Politics in Latin America, 2015
Institutional trust is often measured by several items that are analyzed individually or as sum-scores. However, it is difficult to summarize the results of individual-items analyses, whereas sum-scores may be meaningless if the dimensions that the items
Troy Devon Thomas   +3 more
doaj  

The Episodic, Precessing Giant Molecular Outflow from IRAS 04239+2436 (HH 300) [PDF]

open access: yes, 2001
We present the first set of detailed molecular line maps of the region associated with the giant Herbig-Haro flow HH 300, from the young star IRAS 04239+2436. Our results indicate that the red lobe of the HH 300 flow is depositing a fair amount of momentum and kinetic energy over a notable volume of its host dark cloud.
arxiv   +1 more source

Real‐world evidence concerning clinical and economic outcomes of switching to insulin glargine 300 units/mL vs other basal insulins in patients with type 2 diabetes using basal insulin

open access: yesDiabetes, obesity and metabolism, 2018
This retrospective cohort study compared real‐world clinical and healthcare‐resource utilization (HCRU) data in patients with type 2 diabetes using basal insulin (BI) who switched to insulin glargine 300 units/mL (Gla‐300) or another BI.
F. Zhou   +8 more
semanticscholar   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

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