Results 51 to 60 of about 2,407,583 (266)
Vietnam: Economic Strategy and Economic Reality
Journal of Current Southeast Asian Affairs, 2016 The paper examines the nature of the growing Vietnamese economy and its changing structural characteristics and contrasts this with two core elements of official thinking.
Adam Fforde
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Low-Level Corruption Tolerance: An “Action-Based†Approach for Peru and Latin America
Journal of Politics in Latin America, 2015 Since the beginning of the past decade, the tolerance of corruption by citizens of most Latin American countries has become a concept in its own right within the broader study of corruption. This construct, however, lacks a systematic approach and is yet
Joseph Pozsgai Alvarez
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Journal of Politics in Latin America, 2012 This essay calls for a more nuanced analysis of the evolution of party systems in Latin America. First, I contend that the general impression that party systems are collapsing in Latin America and that processes of partisan and electoral dealignment are ...
Miguel Carreras
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Book Review: Mertha, Andrew: Brothers in Arms: Chinese Aid to the Khmer Rouge, 1975–1979
Journal of Current Southeast Asian Affairs, 2015 Book Review of the Monograph: Mertha, Andrew (2014), Brothers in Arms: Chinese Aid to the Khmer Rouge, 1975–1979.
Chow Bing NGEOW
doaj
The document titled 'LPI LPI 300-300 PDF' provides an in-depth exploration of the LPI 300-300 certification, focusing on essential knowledge areas and competencies required for Linux professionals. This PDF includes comprehensive study materials, exam details, practical examples, and best practices designed to assist candidates in preparing for the ...
openaire +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source