Results 51 to 60 of about 9,598,974 (290)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Role of Religion and Ethnicity in Jakarta’s 2012 Gubernatorial Election

open access: yesJournal of Current Southeast Asian Affairs, 2014
The victory of Joko Widodo (‘Jokowi’) in Jakarta’s 2012 gubernatorial election has been described as a “triumph of democracy” as Joko and his running mate Basuki Tjahaja Purnama (‘Ahok’), a Chinese Christian, successfully won the election ...
Ken Miichi
doaj  

A Cartan type identity for isoparametric hypersurfaces in symmetric spaces

open access: yes, 2002
In this paper, we obtain a Cartan type identity for curvature-adapted isoparametric hypersurfaces in symmetric spaces of compact type or non-compact type.
Koike, Naoyuki
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Burmese Attitude toward Chinese: Portrayal of the Chinese in Contemporary Cultural and Media Works

open access: yesJournal of Current Southeast Asian Affairs, 2012
This paper argues that since at least the mid 1980s, there has been an observable negative attitude among the people of Burma against the Chinese. Such sentiment is not just transient public opinion, but an attitude.
Min Zin
doaj  

Quality-testing the legal Internet: finding law with the SOSIG Law Gateway [PDF]

open access: yes, 2001
English language version of a preprint of an article by Steven Whittle, Information Systems Manager at the Institute of Advanced Legal Studies, published in Recht Bibliothek Dokumentation, the journal of the AjBD Arbeitsgemeinschaft für juristisches ...
Whittle, Steven
core  

Development of a multistage laser frequency stabilization for an interferometric gravitational-wave detector [PDF]

open access: yes, 2003
Laser frequency stabilization is essential for interferometric gravitational-wave detectors to attain their target sensitivity. We have designed a multistage laser frequency stabilization system which has been applied in the development of the TAMA 300 ...
Barton, Mark A., Nagano, Shigeo
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

I Want It All, and I Want It Now: The Political Manipulation of Argentina’s Provincial High Courts I Want It All, and I Want It Now: La manipulación política de las Cortes Supremas provinciales en Argentina

open access: yesJournal of Politics in Latin America, 2012
Provincial supreme courts are important players in local politics because justices can affect the interest of the ruling governors; however, no research has addressed the factors that affect judicial turnover in provincial high courts in new democracies.
Andrea Castagnola
doaj  

Microwave-mediated synthesis of N-methyliminodiacetic acid (MIDA) boronates [PDF]

open access: yes, 2014
A library of over 20, mainly aryl or heteroaryl, N-methyliminodiacetic acid (MIDA) boronates have been synthesised. A rapid microwave-mediated (MW) method (5–10 min) has been developed using polyethylene glycol 300 (PEG 300) as solvent.
Close, Adam J   +3 more
core   +1 more source

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