Results 21 to 30 of about 2,375,149 (311)

miR-370-3p Regulates Adipogenesis through Targeting Mknk1

open access: yesMolecules, 2021
Excessive fat accumulation can lead to obesity, diabetes, hyperlipidemia, atherosclerosis, and other diseases. MicroRNAs are a class of microRNAs that regulate gene expression and are highly conserved in function among species.
Peiwen Zhang   +14 more
doaj   +1 more source

miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker

open access: yesMolecular Therapy: Nucleic Acids, 2018
In the last decade, microRNAs (miRs) have been described as biomarkers and therapeutic agents. Based on this finding, our aim here is to know if (1) miRNA-370-3p can be used as a biomarker associated with a favorable survival and if (2) miRNA-370-3p can ...
Arulraj Nadaradjane   +6 more
doaj   +1 more source

Neuraminidase (NA) 370-Loop Mutations of the 2009 Pandemic H1N1 Viruses Affect NA Enzyme Activity, Hemagglutination Titer, Mouse Virulence, and Inactivated-Virus Immunogenicity

open access: yesViruses, 2022
Hemagglutinin (HA) and neuraminidase (NA) are the two major envelope proteins of influenza viruses. The spatial organization of HA and NA on the virus surface needs to be optimized to promote viral fitness, host specificity, transmissibility, infectivity,
Ting-Hsuan Chen   +2 more
doaj   +1 more source

Random excitation of a system with bilinear hysteresis [PDF]

open access: yes, 1960
An analysis is made of the response of a system with bilinear hysteresis to random excitation. It is shown that for moderately large inputs, the additional damping created by the bilinear hysteresis decreases the mean squared deflection compared with ...
Caughey, T. K.
core   +1 more source

Extramedullary Acute Leukemia—Still an Unforeseen Presentation

open access: yesHematology Reports, 2022
Myeloid sarcomas (MS) are rare extramedullary (EM) hematological tumors that generally arise during the natural course of acute myeloid leukemia (AML), occurring concomitantly with the onset of systemic leukemia; it can also occur following onset but ...
Dina Rochate   +6 more
doaj   +1 more source

The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia

open access: yesMolecular Cancer, 2012
Background Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis.
Zhang Xiaolu   +8 more
doaj   +1 more source

Circ_0035292 knockdown alleviates lipopolysaccharide (LPS)‐induced WI‐38 cell apoptosis and inflammatory injury

open access: yesImmunity, Inflammation and Disease, 2023
Background Circular RNAs have emerged as important regulators in the pathogenesis of human diseases, including infantile pneumonia (IP). In this study, we aimed to explore the effects of circ_0035292 on lipopolysaccharide (LPS)‐treated Wistsar Institute (
Ying Guo, Zhouzhen Li, Chen Cheng
doaj   +1 more source

Isolation and characterization of microsatellite loci from two inbreeding bark beetle species (Coccotrypes) [PDF]

open access: yes, 2003
We developed 14 microsatellite markers in Coccotrypes carpophagus and 14 in C. dactyliperda. These loci will be used for studying genetic structure and the level of inbreeding in populations in the Canary Islands and Madeira.
Armour JAL   +9 more
core   +1 more source

Circ_002117 binds to microRNA-370 and promotes endoplasmic reticulum stress-induced apoptosis in gastric cancer

open access: yesCancer Cell International, 2020
Background Mounting evidence implicates circular RNAs (circRNAs) in various biological processes during cancer progression. Gastric cancer is a main cause of cancer-related deaths worldwide.
Nan Zhou   +5 more
doaj   +1 more source

Silencing of long non-coding RNA KCNQ1OT1 alleviates LPS-induced lung injury by regulating the miR-370-3p/FOXM1 axis in childhood pneumonia

open access: yesBMC Pulmonary Medicine, 2021
Purpose Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.
Ping Wang   +3 more
doaj   +1 more source

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