Results 41 to 50 of about 442,031 (245)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Section images from IODP Hole 370-C0023A

, 2018
Section images from IODP Hole 370 ...
Verena B Heuer (6960776), Yuki Morono (6969194), Expedition 370 Scientists, Lena Maeda (5927063), Expedition 370 Scientists (6969200), Maeda, Lena, Heuer, Verena B, Inagaki, F, Y Kubo (6969197), Kubo, Y, F Inagaki (6969191), Morono, Yuki   +11 more
core   +1 more source

CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis

Cardiovascular Therapeutics, 2022
Background. Circular RNA Transformation/Transcription Domain Associated Protein (circTRRAP, hsa_circ_0081241) was abnormally upregulated in acute myocardial infarction (AMI) patients. However, its biological role and functional mechanism in AMI remain to
Yuan Zhang, Zhenggong Li, Jiao Wang, Hao Chen, Rui He, Hongkun Wu   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Microphotos from IODP Hole 370-C0023A

, 2018
Microphotos from IODP Hole 370 ...
Verena B Heuer (6960776), Yuki Morono (6969194), Expedition 370 Scientists, Lena Maeda (5927063), Expedition 370 Scientists (6969200), Maeda, Lena, Heuer, Verena B, Inagaki, F, Y Kubo (6969197), Kubo, Y, F Inagaki (6969191), Morono, Yuki   +11 more
core   +1 more source

Trends and level of development: View to new eu members

Journal of Business Economics and Management, 2004
The paper deals with evaluation of development level of new European Union members and 3 acceding counties. Authors elaborate existing systems of indicators and modern ranking methods used for indicated purpose.
Vanda Gineviciene, Manuela Tvaronaviciene   +1 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Electrical conductivity from IODP Hole 370-C0023A

, 2018
Electrical conductivity from IODP Hole 370 ...
Verena B Heuer (6960776), Yuki Morono (6969194), Expedition 370 Scientists, Lena Maeda (5927063), Expedition 370 Scientists (6969200), Maeda, Lena, Heuer, Verena B, Inagaki, F, Y Kubo (6969197), Kubo, Y, F Inagaki (6969191), Morono, Yuki   +11 more
core   +1 more source

Inward and outward FDI in Lithuania and Estonia: Review of patterns in neighboring countries

Journal of Business Economics and Management, 2005
The paper aims to trace how important state policies, cultural differences and neighborhood of developed countries are as driving forces attracting foreign capital inflows.
Romualdas Ginevičius, Manuela Tvaronavičiene   +1 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source