Results 211 to 220 of about 609,890 (261)

Tunable hydrogel networks by varying secondary structures of hydrophilic peptoids provide viable 3D cell culture platforms for hMSCs.

Biomater Sci
Pineda-Hernandez A, Castilla-Casadiego DA, Morton LD, Giordano-Nguyen SA, Halwachs KN, Rosales AM.   +5 more
europepmc   +1 more source

A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis

Teworte S, Behrens MC, Widhe M, Gurzeler L, Hedhammar M, Luciani P.   +5 more
europepmc   +1 more source

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Electromolding for 3D cell culture

10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2015
Constructing microstructures with crosslinkable biomaterials, gelatin methacrylate (GelMA) and poly(ethylene glycol) diacrylate (PEGDA), containing fibroblasts (NIH-3T3) are demonstrated using electromolding that combines electrowetting and dielectrophoresis on an electromicrofluidic platform without physical molds.
Yi-Han Lai, Shih-Kang Fan
openaire   +1 more source

Introduction to 3D Cell Culture

2021
This chapter explains the importance of 3D cell culture and highlights its potential and benefits in comparison to traditional 2D cultivation. Since 3D cell culture is supposed to mimic the in vivo situation, we will also have a close look on the complex composition of the in vivo microenvironment and why 2D cultivation does not resemble the in vivo ...
Dominik Egger, Sabrina Nebel
openaire   +1 more source

Vascularization in 3D Cell Culture

2021
The two-dimensional (2D) monoculture does not recapitulate the three-dimensional (3D) environment of in vivo vasculature. Endothelial cell (ECs) spheroids have been introduced as a 3D in vitro model exhibiting angiogenic responses and sprouting behavior in vivo.
M. Markou, D. Kouroupis, T. Fotsis, E. Bagli, C. Murphy   +4 more
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A 3D cell culture approach for studying neuroinflammation

Journal of Neuroscience Methods, 2021
Neurodegenerative diseases are highly complex making them challenging to model in cell culture. All cell types of the brain have been implicated as exerting an effect on pathogenesis, and disease progression is likely influenced by the cross-talk between the different cell types.
James A. Carroll, Simote T. Foliaki, Cathryn L. Haigh   +2 more
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Hydrogels for 3D Cell Culture

2021
One of the fast growing 3D mammalian cell culture platforms are hydrogels—three-dimensional, crosslinked networks of polymers. In this chapter we describe the fundamentals of hydrogels and provide an overview of sources from which hydrogels can be derived, such as animal, non-animal, synthetic, or combinations.
Antonina Lavrentieva, Jane Spencer-Fry
openaire   +1 more source

3D Cell Culture: An Introduction

2017
3D cell culture is an invaluable tool in developmental, cell, and cancer biology. By mimicking crucial features of in vivo environment, including cell-cell and cell-extracellular matrix interactions, 3D cell culture enables proper structural architecture and differentiated function of normal tissues or tumors in vitro.
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Mucus-producing 3D cell culture models

Advanced Drug Delivery Reviews, 2021
In vitro cell-based models have been used for a long time since they are normally easily obtained and have an advantageous cost-benefit. Besides, they can serve a variety of ends, from studying drug absorption and metabolism to disease modeling. However, some in vitro models are too simplistic, not accurately representing the living tissues.
Maria, Helena Macedo, Ana, Baião, Soraia, Pinto, Andreia S, Barros, Helena, Almeida, Andreia, Almeida, José, das Neves, Bruno, Sarmento   +7 more
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Viscoelastic hydrogels for 3D cell culture

Biomaterials Science, 2017
This mini-review discusses newly developed approaches to tuning hydrogel viscoelasticity and recent studies demonstrating an impact of viscoelasticity on cells.
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