Results 1 to 10 of about 668,339 (308)
Cells, 2020 Much interest has been directed towards stem cells, both in basic and translational research, to understand basic stem cell biology and to develop new therapies for many disorders.
Joni H. Ylostalo
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The challenge of ovarian tissue culture: 2D versus 3D culture [PDF]
Journal of Ovarian Research, 2021 Background Cryopreservation of ovarian tissue is a powerful technique for preserving female fertility, as it can restore fertility and endocrine function.
Ana Sofia Pais +6 more
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3D Culture of MSCs for Clinical Application. [PDF]
Bioengineering (Basel)Mesenchymal stem cells (MSCs) play an important role in regenerative medicine and drug discovery due to their multipotential differentiation capabilities and immunomodulatory effects. Compared with traditional 2D cultures of MSCs, 3D cultures of MSCs have emerged as an effective approach to enhance cell viability, proliferation, and functionality, and ...
Gao Q +10 more
europepmc +4 more sources
A new inject-embed 3D culture method enables the spheroid and aggregate formation from single or dual liver cancer cell types [PDF]
Cancer Cell InternationalBackground Three-dimensional (3D) cell culture techniques have emerged as a bridge between traditional two-dimensional (2D) cell culture and the complex 3D architecture of living organisms.
Hanyuan Zhang +9 more
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Validation of a novel perfusion bioreactor system in cancer research [PDF]
Hemijska Industrija, 2020 Development of drugs is a complex, time- and cost-consuming process due to the lack of standardized and reliable characterization techniques and models. Traditionally, drug screening is based on in vitro analysis using two-dimensional (2D) cell cultures ...
Stojkovska Jasmina +5 more
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3D LENSFREE MICROSCOPY FOR 3D CELL CULTURE [PDF]
, 2016 New microscopes are needed to help realize the full potential of 3D organoid culture studies by gathering large quantitative and systematic data over extended period of time while preserving the integrity of the living sample. In order to reconstruct large volume while keeping the ability to catch every single cell, we propose new imaging platforms ...
Berdeu, Anthony +5 more
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Vascularization in 3D Cell Culture [PDF]
, 2021 The two-dimensional (2D) monoculture does not recapitulate the three-dimensional (3D) environment of in vivo vasculature. Endothelial cell (ECs) spheroids have been introduced as a 3D in vitro model exhibiting angiogenic responses and sprouting behavior ...
Bagli, E. +9 more
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Current Advances in 3D Dynamic Cell Culture Systems [PDF]
, 2022 The traditional two-dimensional (2D) cell culture methods have a long history of mimicking in vivo cell growth. However, these methods cannot fully represent physiological conditions, which lack two major indexes of the in vivo environment; one is a ...
Yinghong Zhou +28 more
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Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms
Molecules, 2020 Human induced pluripotent stem cells (hiPSCs) have transformed conventional drug discovery pathways in recent years. In particular, recent advances in hiPSC biology, including organoid technologies, have highlighted a new potential for neural drug ...
Agustín Cota-Coronado +4 more
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Negative regulation of CDKN1A by the histone methyltransferase EHMT2 for cell growth in colorectal cancer [PDF]
Organoid, 2022 Background Epigenetic regulation of oncogenes and tumor suppressor genes by histone methyltransferases is an important process for colon cancer growth and metastasis.
Kwangho Kim +3 more
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