Results 11 to 20 of about 668,339 (308)

Two-Photon Polymerisation 3D-Printing of Microfluidic Neuronal Culture Devices (STL MODEL) [PDF]

open access: yes, 2023
This repository contains the stereolithography (STL) file that describes the surface geometry of the three-dimensional micron scale mold for preparation of modular neuronal culture device, as described in JoVe publication "Two-Photon Polymerisation 3D ...
Noselli Giovanni   +2 more
core   +1 more source

Cell culture models for SARS-CoV-2 infectivity and systemic complications [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
COVID-19 was declared by WHO as a pandemic since March 2020. The vaccination program has been implemented worldwide. Specific antiviral drugs such as remdesivir, molnupiravir and ritonavir-based nirmatrelvir were effective against SARS-CoV-2 infection ...
Khanit Sa-ngiamsuntorn   +3 more
doaj   +1 more source

Plocabulin Displays Strong Cytotoxic Activity in a Personalized Colon Cancer Patient-Derived 3D Organoid Assay

open access: yesMarine Drugs, 2019
Plocabulin is a novel microtubule-disrupting antitumor agent of marine origin that is currently undergoing phase II clinical trials. Plocabulin has potent antiproliferative and antiangiogenic actions in carcinoma cell lines and has antitumor activity in ...
Alba Costales-Carrera   +6 more
doaj   +1 more source

Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model

open access: yesNanomaterials, 2020
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures.
Elisabeth Elje   +7 more
doaj   +1 more source

Maintenance of human adipose derived stem cell (hASC) differentiation capabilities using a 3D culture [PDF]

open access: yes, 2017
In this study, 3D culture system for human adipose-derived stem cell (hASC) using a BioLevitator as the bioreactor for microcarrier-based cultures was established. During the culturing period, hASCs preferred to grow in crevices between microcarriers and
鄭乃禎   +1 more
core   +1 more source

The Importance of Proper Oxygenation in 3D Culture [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Cell culture typically employs inexpensive, disposable plasticware, and standard humidified CO2/room air incubators (5% CO2, ∼20% oxygen). These methods have historically proven adequate for the maintenance of viability, function, and proliferation of many cell types, but with broad variation in culture practices.
Hubert M. Tse   +4 more
openaire   +3 more sources

Walking-Induced Bone Strain Stimulates Cultured Osteoblasts Accompanied by the Low-Magnitude, High Frequency Components

open access: yesJournal of Biomechanical Science and Engineering, 2009
The purpose of this study is to test a hypothesis that involvement of the low-magnitude, high frequency strain components in the walking-induced bone strain is essential to elicit the osteogenic response of osteoblasts to the bone strain.
Shigeo M. TANAKA, Hui B. SUN
doaj   +1 more source

The Stabilization Effect of Mesenchymal Stem Cells on the Formation of Microvascular Networks in a Microfluidic Device

open access: yesJournal of Biomechanical Science and Engineering, 2013
There is a demand for three-dimensional (3D) angiogenesis model including endothelial cells (ECs) and mesenchymal stem cells (MSCs), which are known to differentiate into pericytes, to construct stabilized and matured microvascular networks in vitro ...
Kyoko YAMAMOTO   +8 more
doaj   +1 more source

Developing a 3D culture model to study astrocyte-mediated clearance of protein aggregates [PDF]

open access: yes, 2023
reservedAstrocytes are glial cells that play important roles in central nervous system (CNS) homeostasis and function. In the past decades, astrocytes emerged as phagocytic cells of the brain, assisting microglia in the clearance of extracellular ...
SALVUCCI, MARIA ESTER
core  

3D-printed scaffolds with perfusable channels for low-cost large construct 3D cell culture [PDF]

open access: yes, 2023
662665This study presents a novel approach for threedimensional (3D) cell culture using a two-component system consisting of a 3D-printed scaffold structure combined with a perfusion channel.
Klaus Kreuels   +7 more
core   +1 more source

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