Results 171 to 180 of about 617,855 (266)

Hyaluronic acid-ornithine crosslinked hydrogel as a superior 3D culture platform for high-quality exosome production in advanced wound healing. [PDF]

Stem Cell Res Ther
Qu S, Zhao R, Li K, Tan Y, Li P, Liu B, Yang J, Zhou W.   +7 more
europepmc   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Nanoengineered 3D culture substrate enables superior persistence and polyclonal engraftment of genetically engineered hematopoietic stem cells.

Cell Stem Cell
Midena F, Alessandrini L, Conci C, Barcella M, Gazzo F, Jacchetti E, Carsana E, Benedicenti F, Vacca R, Della Volpe L, Arévalo S, Giannetti K, Barozzi D, Franchino M, Zonari E, Ferrua F, Farina G, Brombin C, Cugnata F, Fiumara M, Tavella T, Cherubin L, Fraschetta F, Cerullo G, Osellame R, Radrizzani M, Ferrari S, Merelli I, Gentner B, Scielzo C, Brendolan A, Naldini L, Aiuti A, Montini E, Raimondi MT, Di Micco R.   +35 more
europepmc   +1 more source

A Robust Marine Collagen Peptide-Agarose 3D Culture System for In Vitro Modeling of Hepatocellular Carcinoma and Anti-Cancer Therapeutic Development. [PDF]

Mar Drugs
Rajbongshi L, Kim JE, Lee JE, Lee SR, Hwang SY, Kim Y, Hong YM, Oh SO, Kim BS, Lee D, Yoon S.   +10 more
europepmc   +1 more source

Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites

Advanced Functional Materials, EarlyView.
Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer, Jan Mathis Hornbostel, Richard Prediger, Sebastian Kluck, Michael Daub, Cornelia Lee‐Thedieck, Frederik Kotz‐Helmer   +6 more
wiley   +1 more source

Nanofibrillar Cellulose Hydrogels with Anionic Surface Modifications for Modulating Macrophage Phenotype in 3D Culture. [PDF]

ACS Appl Mater Interfaces
Heilala M, Turpin R, Pahimanolis N, Nonappa, Ikkala O, Klefström J, Munne PM.   +6 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Development of a digital analysis system for a novel 3D culture-based colony formation to detect malignantly transformed cells in human cell-based therapeutic products. [PDF]

Regen Ther
Kusakawa S, Yang T, Sawada R, Kato R, Sato Y, Yasuda S.   +5 more
europepmc   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Advancements in photobiomodulation for generating functional beta cells from adipose derived stem cells in 3D culture: a comprehensive review. [PDF]

Stem Cell Res Ther
Daramola O, Abrahamse H, Crous A.
europepmc   +1 more source