Results 241 to 250 of about 668,339 (308)

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

Nanoengineered 3D culture substrate enables superior persistence and polyclonal engraftment of genetically engineered hematopoietic stem cells.

Cell Stem Cell
Midena F, Alessandrini L, Conci C, Barcella M, Gazzo F, Jacchetti E, Carsana E, Benedicenti F, Vacca R, Della Volpe L, Arévalo S, Giannetti K, Barozzi D, Franchino M, Zonari E, Ferrua F, Farina G, Brombin C, Cugnata F, Fiumara M, Tavella T, Cherubin L, Fraschetta F, Cerullo G, Osellame R, Radrizzani M, Ferrari S, Merelli I, Gentner B, Scielzo C, Brendolan A, Naldini L, Aiuti A, Montini E, Raimondi MT, Di Micco R.   +35 more
europepmc   +1 more source

The Effect of Liposomal DMU-212 on the Differentiation of Human Ovarian Granulosa Cells in a Primary 3D Culture Model. [PDF]

Pharmaceuticals (Basel)
Jόzkowiak M, Wawrzyniak D, Kawczyńska A, Skupin-Mrugalska P, Czajkowski M, Mozdziak P, Podralska M, Żywicki M, Kempisty B, Spaczyński RZ, Piotrowska-Kempisty H.   +10 more
europepmc   +1 more source

Mimetic Core‐Sheath Silk Sutures with Superior‐Strength for Pain Management, Anti‐Infection and Wound Healing

Advanced Healthcare Materials, EarlyView.
ABSTRACT Sutures are crucial for tissue approximation and wound healing. Besides their strength limits requirement, they often fail to effectively address complications like infection and pain. Inspired by natural silk's “core‐sheath” structure, our suture features a wet‐spun core of n zinc‐fortified silk fibroin fibers (RSF‐Zn2+) after drawing with ...
Yi Peng, Kai Ma, Xiaoxiao Li, Xiaozhuo Wu, Yuezhou Zhang, Ying Luo, Chenxing Zhang, Wen Zhong, Chunjing Yu, Lin Lu, Malcolm Xing, Guozhong Lyu   +11 more
wiley   +1 more source

Hyaluronic acid-ornithine crosslinked hydrogel as a superior 3D culture platform for high-quality exosome production in advanced wound healing. [PDF]

Stem Cell Res Ther
Qu S, Zhao R, Li K, Tan Y, Li P, Liu B, Yang J, Zhou W.   +7 more
europepmc   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

A Robust Marine Collagen Peptide-Agarose 3D Culture System for In Vitro Modeling of Hepatocellular Carcinoma and Anti-Cancer Therapeutic Development. [PDF]

Mar Drugs
Rajbongshi L, Kim JE, Lee JE, Lee SR, Hwang SY, Kim Y, Hong YM, Oh SO, Kim BS, Lee D, Yoon S.   +10 more
europepmc   +1 more source

The maintenance of culture environment in 3D suspension culture

Iryou kikigaku (The Japanese journal of medical instrumentation), 2015
openaire   +2 more sources

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Protocol for generating a 3D culture of epiblast stem cells. [PDF]

STAR Protoc
Rosa VS, Sato N, Shahbazi MN.
europepmc   +1 more source