Results 251 to 260 of about 5,851,651 (312)

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Development of a sustainable strategy for cultured fat production based on serum-free 3D culture of bovine adipose stem cells. [PDF]

Sci Rep
Xuan Z, Peng Q, Borsuk M, Prasad R, Zachar V, Das SK, Pennisi CP.   +6 more
europepmc   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Methods for Evaluating the Effects of 2D and 3D Culture Environment on Macrophage Response to Mycobacterium Infection. [PDF]

Microorganisms
Stolley DL, Rasaputra KS, May EE.
europepmc   +1 more source

The maintenance of culture environment in 3D suspension culture

Iryou kikigaku (The Japanese journal of medical instrumentation), 2015
openaire   +2 more sources

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Gelatin-methacryloyl hydrogel stiffness influences epithelial-mesenchymal transition in MCF7 but not MDA-MB-231 breast cancer cells in 3D culture. [PDF]

Biol Open
Wise JA, Currie MJ, Woodfield TBF, Lim KS, Phillips E.   +4 more
europepmc   +1 more source

The role of 3D culture models and advanced chromatography in exosome research for triple-negative breast cancer. [PDF]

J Egypt Natl Canc Inst
Sheikh M, Bagga H, Bhojwani Y, Telrandhe U.   +3 more
europepmc   +1 more source

Impact of different 3D culture environments on spheroid morphology, drug response, and invasion in pancreatic cancer cells. [PDF]

BMC Res Notes
Karakas D, Sigirli S.
europepmc   +1 more source

Three-dimensional (3D) culture-primed placental mesenchymal stem cells decrease cellular heterogeneity, significantly enhancing osteogenesis via improving mitochondrial function. [PDF]

Mater Today Bio
Wang LT, Yen BL, Wang HH, Lin YF, Liao CY, Hsu PJ, Yen ML.   +6 more
europepmc   +1 more source