Results 101 to 110 of about 1,005,614 (301)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Panoramic Images for Situational Awareness in a 3D Chart-of-the-Future Display [PDF]

, 2005
Many early charts featured sketches of the coastline, providing a good picture of what the shore looked like from the bridge of a ship. These helped the mariner to distinguish one port from another during an approach and establish their rough position ...
Arsenault, Roland J., Brennan, Rick, Plumlee, Matthew D, Ware, Colin   +3 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

An Optimal 3D Visualization Method for Integral Imaging Optical Display Systems Using Depth Rescaling and Field-of-View Resizing

Applied Sciences
Integral imaging is a promising 3D sensing and visualization technique that enables full-parallax and continuous viewpoint reconstruction. However, challenges, such as depth distortion and a limited field-of-view (FoV), can compromise the quality of 3D ...
Xin Shen, Nathan Green, Vanden Haviland
doaj   +1 more source

Review of Organic Photorefractive Materials and Their Use for Updateable 3D Display. [PDF]

Materials (Basel), 2021
Blanche PA, Ka JW, Peyghambarian N.
europepmc   +1 more source

From pixel to mesh: accurate and straightforward 3D documentation of cultural heritage from the Cres/Lošinj archipelago [PDF]

, 2015
Most people like 3D visualizations. Whether it is in movies, holograms or games, 3D (literally) adds an extra dimension to conventional pictures. However, 3D data and their visualizations can also have scientic archaeological benets: they are crucial in ...
Doneus, Michael, Doneus, Nives, Verhoeven, Geert, Štuhec, Seta   +3 more
core  

Disorder driven phase transitions of the large q-state Potts model in 3d

, 2005
Phase transitions induced by varying the strength of disorder in the large-q state Potts model in 3d are studied by analytical and numerical methods.
, , Aizenman M., Anglès d'Auriac J.-Ch., Ballesteros H. G., Chatelain C., D. Stauffer, F Iglói, Harris A. B., Iglói F., J.-Ch. Anglès d'Auriac, Kasteleyn P. W., M. T Mercaldo, Rieger H., Rieger H.   +14 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Tunable liquid crystal grating based holographic 3D display system with wide viewing angle and large size. [PDF]

Light Sci Appl, 2022
Li YL, Li NN, Wang D, Chu F, Lee SD, Zheng YW, Wang QH.   +6 more
europepmc   +1 more source