Results 141 to 150 of about 660,620 (286)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

3D Modelling for Photonic Crystal Structure in Papilio maackii Wing Scales. [PDF]

Materials (Basel), 2022
Yang S, Wang Y, Gao W.
europepmc   +1 more source

3D Face Appearance Model

, 2006
We build a 3d face shape model, including inter- and intra-shape variations, derive the analytical jacobian of its resulting 2d rendered image, and show example of its fitting performance with light, pose, id, expression and texture variations.}
Lading, Brian, Larsen, Rasmus, Astrom, K
openaire   +2 more sources

Modelling 3-Dimensional cadastral boundaries in a BIM environment: a case study using volumetric format plans in Queensland, Australia

International Journal of Digital Earth
The future vision for cadastre in many jurisdictions is to deliver a digital representation of legal and physical dimensions of the real world that is survey accurate, 3D, and dynamic.
Ben Bryant, Armin Agha Karimi, Behnam Atazadeh, Abbas Rajabifard   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Can 3D imaging modeling recognize functional tissue and predict liver failure? A retrospective study based on 3D modelling of the major hepatectomies after hepatic modulation. [PDF]

BMC Surg, 2023
Vicente E, Quijano Y, Duran H, Diaz E, Fabra I, Malave L, Ruiz P, Pizzuti G, Naldini C, De Nobili G, Caruso R, Ferri V.   +11 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Editorial: 3D Modelling of Mammalian Embryos and Organs. [PDF]

Front Cell Dev Biol, 2021
Garagna S, Cebral E, Aréchaga J, Zuccotti M.   +3 more
europepmc   +1 more source

Review of the state of practice in geovisualization in the geosciences

Frontiers in Earth Science
Geosciences modelling and 3D geovisualization is growing and evolving rapidly. Driven by commercial urgency and an increase in data from sensor-based sources, there is an abundance of opportunities to analyze geosciences data in 3D and 4D.
Mia Fitzpatrick, Nick Hedley
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source