Results 141 to 150 of about 760,415 (358)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

cudaMMC: GPU-enhanced multiscale Monte Carlo chromatin 3D modelling. [PDF]

Bioinformatics, 2023
Wlasnowolski M, Grabowski P, Roszczyk D, Kaczmarski K, Plewczynski D.   +4 more
europepmc   +1 more source

3D modelling and simulation of the impact of wearing a mask on the dispersion of particles carrying the SARS-CoV-2 virus in a railway transport coach. [PDF]

Sci Rep, 2023
Armand P, Tâche J.
europepmc   +2 more sources

Certifiable 3D Object Pose Estimation: Foundations, Learning Models, and Self-Training [PDF]

, 2022
Rajat Talak, Lisa Peng, Luca Carlone
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

3D modelling of γδ T-cell immunotherapy. [PDF]

Clin Transl Med, 2022
Hull CM, Maher J.
europepmc   +1 more source

Hybrid 2D and 3D face verification [PDF]

, 2007
Face verification is a challenging pattern recognition problem. The face is a biometric that, we as humans, know can be recognised. However, the face is highly deformable and its appearance alters significantly when the pose, illumination or expression ...
McCool, Christopher Steven
core   +1 more source

Peer Review #3 of "Syntactic model-based human body 3D reconstruction and event classification via association based features mining and deep learning (v0.2)"

, 2021
Gaurav Tiwari
openalex   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Simulating movements of daily living in robot-assisted total hip arthroplasty with 3D modelling. [PDF]

Bone Jt Open, 2023
Tung WS, Donnelley C, Eslam Pour A, Tommasini S, Wiznia D.   +4 more
europepmc   +1 more source