Results 141 to 150 of about 140,547 (317)

Universal attraction force-inspired freeform surface modeling for 3D sketching [PDF]

open access: yes, 2006
This paper presents a novel freeform surface modeling method to construct a freeform surface from 3D sketch. The approach is inspired by Newton’s universal attraction force law to construct a surface model from rough boundary curves and unorganized ...
Wright, David   +3 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

3D Modeling

open access: yes
Content: report on the choice of the 3D representation and on the 3D mapping activities. A focus of the performance assessment will be on on accuracy, reliability, and completeness of the reconstructed 3D structure both in terms of usable result for human operators as well as usage in the robotic navigation tasks.
Sander Münster   +12 more
openaire   +3 more sources

An overview of virtual city modelling : emerging organisational issues [PDF]

open access: yes, 2007
This paper presents a recent overview of the increasing use of Virtual Reality (VR) technologies for the simulation of urban environments. It builds on previous research conducted on the identification of three-dimensional (3D) city models and offers an ...
Horne, Margaret   +5 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Modelling 3-Dimensional cadastral boundaries in a BIM environment: a case study using volumetric format plans in Queensland, Australia

open access: yesInternational Journal of Digital Earth
The future vision for cadastre in many jurisdictions is to deliver a digital representation of legal and physical dimensions of the real world that is survey accurate, 3D, and dynamic.
Ben Bryant   +3 more
doaj   +1 more source

Editorial: 3D Modelling of Mammalian Embryos and Organs. [PDF]

open access: yesFront Cell Dev Biol, 2021
Garagna S   +3 more
europepmc   +1 more source

3D urban subsurface modelling and visualisation : a review of good practices and techniques to ensure optimal use of geological information in urban planning [PDF]

open access: yes, 2017
This report is the result of COST Action TU1206 Working Group 2, Work package 2.3, and focusses on 3D urban subsurface modelling and visualisation. The major aims of this report are: 1) evaluating current techniques and identify good practices / best ...
Ganerod, G.V.   +9 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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