Validity of Alfred Step Test Exercise Protocol (A‐STEP) as a Surrogate VO2Max Cardiopulmonary Exercise Test (CPET) to Cycle Ergometry in Adults With Cystic Fibrosis [PDF]
Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.Background The Alfred Step Test Exercise Protocol (A‐STEP) and feasibility study were previously published. The aim here was to determine the validity of the A‐STEP compared to cycle ergometry (CPET) in adults with CF. Methods The A‐STEP and CPET were carried out in random order 2 weeks apart.
Brenda Button +7 more
wiley +2 more sources
Clonal Stabilization Reveals a
The FASEB JournalABSTRACT Hydrogen sulfide (H 2 S) functions as a signaling molecule and cytoprotectant. In many tissues, H 2 S is produced from l ‐cysteine, whereas the kidney also produces H
Akari Miyamoto +4 more
openaire +2 more sources
Hydrogen Sulfide and β-Synuclein Are Involved and Interlinked in the Aging Glaucomatous Retina
Journal of Ophthalmology, 2020 Purpose. Glaucoma, one of the leading causes of irreversible blindness worldwide, is a group of disorders characterized by progressive retinal ganglion cell (RGC) loss.
Hanhan Liu +3 more
doaj +2 more sources
Enzymes that generate and regulate intracellular persulfides and polysulfides: mechanistic insights and inhibitors [PDF]
Frontiers in PhysiologyReactive sulfur species (RSS), which include various persulfides and polysulfides, are generated by multiple enzymes in vivo and play critical roles in mammalian physiological processes such as redox signaling, metabolic regulation, radical scavenging ...
Ko Hirabayashi +6 more
doaj +2 more sources
Clinimetric properties of field exercise tests in cystic fibrosis: a systematic review [PDF]
European Respiratory ReviewObjectives Accurate measurement of exercise capacity is an important prognostic indicator for people with cystic fibrosis (pwCF); however, gold-standard, cardiopulmonary exercise tests are commonly unavailable.
Jennifer Corda +3 more
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Pan-inhibition of the three H2S synthesizing enzymes restrains tumor progression and immunosuppression in breast cancer [PDF]
Cancer Cell InternationalBackground Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC).
Alyaa Dawoud +7 more
doaj +2 more sources
Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging [PDF]
Redox BiologyProtein persulfidation is a significant post-translational modification that involves addition of a sulfur atom to the cysteine thiol group and is facilitated by sulfide species.
Maria-Kyriaki Drekolia +9 more
doaj +2 more sources
The potential role of H2S in the anti-infective function of antimicrobial peptides [PDF]
Nature CommunicationsAntimicrobial peptides (AMPs) are essential components of the innate immune system in animals, playing crucial roles in defending against microbial infections.
Xu Wang +12 more
doaj +2 more sources
Chemistry of Hydrogen Sulfide—Pathological and Physiological Functions in Mammalian Cells [PDF]
Cells, 2023 Hydrogen sulfide (H2S) was recognized as a gaseous signaling molecule, similar to nitric oxide (-NO) and carbon monoxide (CO). The aim of this review is to provide an overview of the formation of hydrogen sulfide (H2S) in the human body.
Celia María Curieses Andrés +4 more
doaj +2 more sources
Physical activity level and physical fitness in subjects with chronic musculoskeletal pain: a cross-sectional study [PDF]
PeerJBackground Low physical activity (PA) levels and low physical fitness (PF) have been reported in subjects with temporality-based chronic pain; however, it is unknown whether there are differences in subjects with nociplastic pain (NP) compared with ...
Gabriel Rojas, Ignacio Orozco-Chavez
doaj +3 more sources