Results 171 to 180 of about 37,025 (306)

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero   +7 more
wiley   +1 more source

Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Astrocyte‐derived lactate enhances neuronal NMDA receptor (NMDAR) function and synaptic plasticity through a redox‐ and CaMKII‐dependent mechanism. Lactate enters neurons via monocarboxylate transporters (MCTs) and is oxidized by lactate dehydrogenase (LDH) to pyruvate, generating NADH and increasing the intracellular NADH/NAD ...
Hubert Fiumelli   +13 more
wiley   +1 more source

Sentience in cephalopod molluscs: an updated assessment

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1311-1333, June 2026.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell   +4 more
wiley   +1 more source

RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi   +10 more
wiley   +1 more source

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

open access: yesReviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source

Rosegadors - 3r PREMI

open access: yesBiologia on-line, 2019
Vaig descobrir que era un ratolí i que em trobava en una gàbia de l’estabulari. Estava sol, però en caixes similars, contigües a la meva, agrupades, que feien la impressió d’una ciutat de rosegadors, un rumor de xiuxiueigs, de cossos remenant les serradures, de minúscules dents mastegant, em feia intuir una multitud d’éssers com jo.
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, Volume 16, Issue 5, Page 944-965, May 2026.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Environmental Sustainability in Wineries: How Contingency Factors and Environmental Management Accounting Tools Influence Environmental Performance?

open access: yesBusiness Strategy and the Environment, Volume 35, Issue 4, Page 5802-5822, May 2026.
ABSTRACT How do wineries design sustainability practices and use environmental management accounting (EMA)? This study addresses that question by analyzing the influence of contingency factors on the adoption of sustainability practices and the use of EMA tools to improve the environmental performance of wineries. The research was carried out through a
Andréia Cittadin   +2 more
wiley   +1 more source

Anxiolytic and Memory Protective Effects of Withanolide D Isolated From Acnistus arborescens in Adult Zebrafish

open access: yesChemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Withanolide D Exhibits Anxiolytic and Memory‐Protective Effects. ABSTRACT This study evaluated the anxiolytic and memory‐protective effects of withanolide D in adult zebrafish (Danio rerio). The compound was administered at doses of 4, 20, and 40 mg/kg and showed no signs of toxicity after 96 h of observation at any of the doses tested.
Cléia Rocha de Sousa Feitosa   +17 more
wiley   +1 more source

Fine‐Scale Temporal Dynamics of the Honey Bee Hive Microbiome and Foraging Revealed by Airborne eDNA

open access: yesEnvironmental DNA, Volume 8, Issue 3, May–June 2026.
Airborne eDNA collected within honey bee hives reveals diverse plant and microbial communities. While richness remains stable, seasonal shifts in plant and microbiome composition highlight dynamic resource use, demonstrating eDNA's potential for non‐invasive, fine‐scale monitoring of foraging and colony health. ABSTRACT Environmental DNA (eDNA) has the
Orianne Tournayre   +6 more
wiley   +1 more source

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