Results 161 to 170 of about 14,239 (267)

Universal‐Bac3Gel: A 3D Biofilm‐Relevant Matrix That Supports In Vitro Growth and Biofilm Formation of ESKAPE Pathogens

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Universal‐Bac3Gel, a 3D biofilm‐relevant matrix with oxygen and nutrient gradients, supports the growth and species‐specific biofilm architectures of all ESKAPE pathogens, offering a physiologically relevant platform for antimicrobial testing and microbiological research. ABSTRACT Human microbiota is increasingly considered to shape health and disease,
Emanuela Peluso, Sebastião van Uden, Sonja Visentin, Paola Petrini, Daniela Peneda Pacheco, Livia Visai   +5 more
wiley   +1 more source

Animal models of critical illness in the Asia-Pacific region: current practices, shared challenges, and future directions. [PDF]

Intensive Care Med Exp
Fujinami Y, Liu S, Bassi GL, Osuchowski M, Yao Y, Fraser J, Inoue S.   +6 more
europepmc   +1 more source

Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy

Small Science, Volume 6, Issue 8, August 2026.
Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik, Urooj Yousaf Virk, Mohamed Salah Attia, Jenny Wilson, Ming Wei   +4 more
wiley   +1 more source

Advancing the 3Rs in bone tissue engineering: emerging <i>in vitro</i>, <i>in silico</i>, and refined <i>in vivo</i> strategies. [PDF]

Front Physiol
Cagle AL, Limberg AK, Anup A, La Croix AE, Hixon KR.   +4 more
europepmc   +1 more source

Mechanistic Study of Platelet Membrane‐Coated Resveratrol Nanosystem in Mitochondrial Dysfunction and Endothelial Senescence During Atherosclerotic Lesion Development via FOXM1 Activation

Aging Cell, Volume 25, Issue 8, August 2026.
Schematic diagram of the mechanism by which PM@RSV NPs alleviate AS via FOXM1 activation. ABSTRACT Atherosclerosis (AS) is closely linked to endothelial cell (EC) senescence and mitochondrial dysfunction, which impair vascular repair. Resveratrol (RSV) has antioxidant, anti‐inflammatory, and pro‐angiogenic effects, but its clinical use is restricted by
Li Xiao, Zexin Zhan, Ping Liu, Bing Qin
wiley   +1 more source

A community-partnered process for construct & measure development: The 3Rs: Reading, Racial equity, & Relationships. [PDF]

Am J Community Psychol
Wanless SB, Orman MC, Moye S, Spear CF.
europepmc   +1 more source

Response to ‘The 3Rs: A student perspective’ [PDF]

Medical Teacher, 2015
Eley, Diann S., Stallman, Helen
openaire   +5 more sources

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, Volume 183, Issue 15, Page 4227-4245, August 2026.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4836-4854, August 2026.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph   +9 more
wiley   +1 more source

Strengthening antimicrobial resistance policies: lessons from the design and implementation phase of the EU-JAMRAI 2 Sustainability Guidance Tool. [PDF]

Public Health Action
Davido B, Kharkhordine M, Merillon D, Fuentes-Braesch M.   +3 more
europepmc   +1 more source