Results 141 to 150 of about 14,239 (267)

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa, Jack R. T. Darby, Stacey L. Holman, Steven K. S. Cho, Ashley S. Meakin, Mitchell C. Lock, Jordan A. Minns, Michael D. Wiese, Christopher K. Macgowan, Mike Seed, Janna L. Morrison   +10 more
wiley   +1 more source

Large Language Models in Preclinical Spine Research: A Scoping Review and Expert Perspective on Evidence‐Aware Experimental Workflows

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background Preclinical spine research is limited by heterogeneous experimental reporting, fragmented documentation, and barriers to reproducibility and translational alignment. Large language models (LLMs) and related artificial intelligence (AI) technologies may support semantic interpretation, structured data extraction, and reasoning over ...
Siegmund Lang, Stefan Motov, Jonas Krueckel, Julian Scherer, Victor E. Staartjes, Karin Wuertz‐Kozak   +5 more
wiley   +1 more source

Artificial Intelligence in Veterinary Neurology: Comparative Insights From Human Medicine and Cross‐Species Technology Transfer

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Overview of major artificial intelligence applications in veterinary neurology, including neuroimaging, seizure prediction, gait and pain assessment, and prognostic modeling. The figure also highlights cross‐species technology transfer and key challenges, such as limited data, lack of standardization, and ethical concerns.
Kianoush Saberi, Rosull Saadoon Abbood, Sarah F. Al‐Taie, Aseel Smerat, Abdullaev Makhmudjon Mukhamedovich, Maksudova Malika Khamdamjonovna, Mohammad Hedayatinia, Arash Zarei, Mehrdad Nourizadeh, Amir Arsalan Ghahari, Mehrdad Neshat Gharamaleki, Fatemeh Malekinejad, Reza Akhavan‐Sigari   +12 more
wiley   +1 more source

Improvement of Mouse Spermatozoa Freezing at −80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, Volume 14, Issue 6, Page 1647-1655, September 2026.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source

Revisiting 3Rs: rethinking replacement and new approach methodologies

Frontiers in Toxicology
Jessica Rosolowski, Tilo Weber, Atena Malakpour-Permlid, Stina Oredsson   +3 more
semanticscholar   +1 more source

SCRAPZON - With 3R’s

International Journal for Research in Applied Science and Engineering Technology
This paper presents New Trend is Scrap consists of recyclable and leftover stuff from the product manufacturing and consumption, such as parts of vehicles, building supplies, newspapers, notebooks, etc. Our vision to divert recyclables from India’s unsanitary landfills.
openaire   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

Acta Ophthalmologica, Volume 104, Issue 6, Page e671-e685, September 2026.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol, Ana Martínez‐Vacas, David García‐Bernal, Manuel Vidal‐Sanz, María Paz Villegas‐Pérez, Diego García‐Ayuso, Johnny Di Pierdomenico   +6 more
wiley   +1 more source

Challenging the Status Quo: Standardisation, Regulation and the Rise of 3D In Vitro Models for a More Humane and Predictive Future in Healthcare

Advanced Therapeutics, Volume 9, Issue 8, August 2026.
Overview of challenges in traditional models and how 3D in vitro models and in silico approaches tackle those, incentivising a collaboration between what is currently an accepted standard, validated and regulated, with the new technologies to ensure faster adoption and translation. (Created with BioRender). ABSTRACT For decades, biomedical research has
Priscila Melo
wiley   +1 more source

HIF‐1α and HIF‐2α Are Upregulated in the Hippocampus but Not in the Medial Prefrontal Cortex in Experimental PTSD

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background Post‐traumatic stress disorder (PTSD) is a psychiatric disorder characterized by anxiety, abnormal stress responses, and pathological memory formation. Research indicates that hypoxia‐inducible pathways might influence the neurobiology of PTSD.
Denys Porkhalo, Denis Pashevin, Yana Naumenko, Victor Dosenko   +3 more
wiley   +1 more source

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2640-2649, August 2026.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source