Results 121 to 130 of about 14,239 (267)

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

Small, EarlyView.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova, Olivera Valentirović Dann, Jennifer B. Schwarzkopf, Tengku I. Maulana, Jamina S. Gerhardus, Leon Kaysan, Katja Meier, Andreas Blaeser, Beate K. Straub, Holger Gerhardt, Ulrike A. Nuber   +10 more
wiley   +1 more source

Principles of the 3Rs and ARRIVE Guidelines in Animal Research

Majalah Kardiologi Indonesia, 2017
The use of animals in research has concerned the general public and thoughtful researchers for a long time. For improved animal welfare and increased research quality, researchers have moral obligations to include the 3Rs.
doaj   +1 more source

A framework for the ethical use of animal‐borne devices in post‐release monitoring following rehabilitation

Wildlife Biology, EarlyView.
Rehabilitation and release contribute to conservation efforts for threatened species. Ensuring that these efforts are effective requires a good understanding of the factors which determine survival and integration of released animals into wild populations.
Jessica Harvey‐Carroll, Daire Carroll, Cara-Marie Trivella, Ellen Connelly   +3 more
wiley   +1 more source

Insights from the Presidential Addresses to the Agricultural Economics Society

Journal of Agricultural Economics, EarlyView.
ABSTRACT The Society's published presidential addresses have embraced a wide range of subject matter, reflecting a ‘road well travelled’ in agricultural economics. The areas covered include the development and use of data and statistics, lessons from history, sectoral analysis, land economics, international trade and international development.
David Blandford
wiley   +1 more source

Sharp force trauma analysis without animal bones: A proposal for sustainable and ethical bone proxies

Journal of Forensic Sciences, EarlyView.
Abstract Sharp force trauma has been the leading cause of homicide in England and Wales for more than a decade. Experimental research on sharp force trauma frequently relies on animal bone as a substitute for human remains, yet their ethical acceptability and comparability to human bone remain contested.
Beth Lawrence, Giada Sciâdi Steiger, Matteo Borrini   +2 more
wiley   +1 more source

A Proposal to Achieve Sustainable Development Goals in the Luxury Fashion Industry

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT The luxury industry stands at a crossroads between tradition and sustainability. The objective of this paper is to analyse the relationship and effects of the luxury fashion industry on the Sustainable Development Goals (SDGs) and identify opportunities to improve its management.
Alicia Parro‐Ruiz, María‐Sonia Medina‐Salgado, Marta Ortiz‐de‐Urbina‐Criado, María Torrejón‐Ramos   +3 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Aligned polycaprolactone/polyaniline electrospun nanofibers for directing neural stem cell differentiation and neuron arrangement

Frontiers in Biomaterials Science
The use of engineered biomimetic substrates combined with neural stem cells (NSCs) constitutes a promising approach to develop reliable in vitro models of the nervous tissue.
Michela Licciardello, Michela Licciardello, Michela Licciardello, Cecilia Traldi, Cecilia Traldi, Cecilia Traldi, Matteo Bortolameazzi, Matteo Bortolameazzi, Matteo Bortolameazzi, Daniele Testore, Daniele Testore, Daniele Testore, Gianluca Ciardelli, Gianluca Ciardelli, Gianluca Ciardelli, Gianluca Ciardelli, Chiara Tonda-Turo, Chiara Tonda-Turo, Chiara Tonda-Turo   +18 more
doaj   +1 more source

Reflections on Traceability for Visualization Research

Computer Graphics Forum, EarlyView.
Abstract Decades of advocacy for reproducibility and replication have advanced open, transparent practices in the sciences. However, traditional notions of reproducibility fit poorly with design‐oriented visualization research, where insights emerge through subjective, situated, and iterative work.
J. Rogers, D. Akbaba, J. S. Brown, A. Lex, M. Meyer   +4 more
wiley   +1 more source

Effect of Membrane Perforations With and Without Collagen Membrane Coverage in Vertical Ridge Augmentation: An Experimental Pilot In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives Given the proposed bioactive role of collagen membranes, we aimed to evaluate whether the perforation size of titanium‐reinforced dPTFE membranes, with or without an additional collagen membrane, influences outcomes of vertical alveolar ridge augmentation (VARA).
Istvan A. Urban, Sándor Farkasdi, Muhammad H. A. Saleh, Monica Lopez, Fernando Muñoz, Gabor Varga, Mauricio G. Araujo, Fabio Vignoletti   +7 more
wiley   +1 more source