Results 21 to 30 of about 13,809 (213)

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide [PDF]

Biochemical Journal, 1997
Hypochlorous acid is the most powerful oxidant generated by neutrophils and is likely to contribute to the damage mediated by these inflammatory cells. The haem enzyme myeloperoxidase catalyses its production from hydrogen peroxide and chloride. 4-Aminobenzoic acid hydrazide (ABAH) is a potent inhibitor of hypochlorous acid production.
A J, Kettle, C A, Gedye, C C, Winterbourn   +2 more
openaire   +2 more sources

High Score of ELST-Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2-i Index. [PDF]

DEN Open
ABSTRACT Background To evaluate the usefulness of the ELST‐blue score to explore its potential application in identifying high‐risk groups for early chronic pancreatitis (ECP) through reflecting on pancreatic elasticity and the reduction of pancreatic function, and we tried to demonstrate whether the ELST‐blue score was significantly associated with ...
Nakamura K, Futagami S, Agawa S, Higashida S, Tanabe T, Onda T, Kawawa R, Habiro M, Kirita K, Sai S, Itokawa N, Ueki N, Watanabe Y, Ohta R, Taniai N, Honda K, Iwakiri K, Atsukawa M.   +17 more
europepmc   +2 more sources

Tuberculostatic Derivatives of 4-Aminobenzoic Acid. IV. Heterocyclic Derivatives of 4-Aminosalicyclic Acid (PAS). [PDF]

Acta Chemica Scandinavica, 1952
Kai Jensen, Svend Å. K. Christensen, Endre Berner, Ernst Finsnes, Jörgine Stene Sörensen, Nils Andreas Sörensen   +5 more
openalex   +2 more sources

4-Aminobenzoic acid–nicotinic acid (2/1)

Acta Crystallographica Section E Structure Reports Online, 2006
In the title compound, 2C7H7NO2·C6H5NO2, the 4-amino­benzoic acid and the nicotinic acid mol­ecules are approximately planar. The crystal structure is stabilized by an extensive network of N—H⋯O, O—H⋯O and O—H⋯N hydrogen bonds.
Samuel Robinson Jebas, Thailampillai Balasubramanian   +1 more
openaire   +1 more source

Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions

Animals, 2021
Neutrophils can originate neutrophil extracellular traps (NETs). Myeloperoxidase (MPO) is a peroxidase found in NETs associated to equine endometrosis and can be inhibited by 4-aminobenzoic acid hydrazide (ABAH).
Ana Amaral, Carina Fernandes, Maria Rosa Rebordão, Anna Szóstek-Mioduchowska, Karolina Lukasik, Pedro Pinto-Bravo, Luís Telo da Gama, Dariusz Jan Skarzynski, Graça Ferreira-Dias   +8 more
doaj   +1 more source

A dinuclear copper complex: bis(μ-4-aminobenzoato)bis[aqua(1,10-phenanthroline)copper(II)] dichloride bis(4-aminobenzoic acid) dihydrate

Acta Crystallographica Section E, 2008
The title complex, [Cu2(C7H6NO2)2(C12H8N2)2(H2O)2]·2C7H7NO2·2H2O, consists of a dinuclear [Cu2(C7H6NO2)2(C12H8N2)2(H2O)2]2+ cation, two Cl− anions, two 4-aminobenzoic acid molecules and two disordered water molecules (site occupancy ...
Miao-Ling Huang, Qing-Fan Xie, Jing-Chun Xian, Yan-Min Chen, Zi-Qiao Zhou   +4 more
doaj   +1 more source

The 1:1 adduct of 4-aminobenzoic acid with 4-aminobenzonitrile [PDF]

Acta Crystallographica Section C Crystal Structure Communications, 2000
The 1:1 adduct of 4-aminobenzoic acid (PABA) with 4-am-inobenzonitrile (PABN), C(7)H(7)NO(2).C(7)H(6)N(2), consists of a primary centrosymmetric cyclic hydrogen-bonded PABA dimer interaction [O.O 2.640 (3) A] peripherally linked into chains by weaker hydrogen bonds via a head-to-tail PABN interaction [N.N 3.179 (4) and N.O 3.062 (4) A], and is linked ...
Smith, Graham, Bott, Raymond, Lynch, Daniel   +2 more
openaire   +3 more sources

4-Aza-1-azoniabicyclo[2.2.2]octane–2-aminobenzoate–2-aminobenzoic acid (1/1/1)

Acta Crystallographica Section E, 2011
A 4-aza-1-azoniabicyclo[2.2.2]octane cation, a 2-aminobenzoate anion and a neutral 2-aminobenzoic acid molecule comprise the asymmetric unit of the title compound, C6H13N2+·C7H6NO2−·C7H7NO2. An intramolecular N—H...O
Hadi D. Arman, Trupta Kaulgud, Edward R. T. Tiekink   +2 more
doaj   +1 more source

The Efficacy of Medical Treatment of Peyronie’s Disease: Potassium Para-Aminobenzoate Monotherapy vs. Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor [PDF]

The World Journal of Men's Health, 2016
Purpose: This study was designed to evaluate the efficacy of medical treatment of Peyronie’s disease. Materials and Methods: A total of 109 patients with Peyronie’s disease who had been treated from January 2011 to December 2014 were retrospectively ...
Tae Yong Park, Hyeong Guk Jeong, Jong Jin Park, Ji Yun Chae, Jong Wook Kim, Mi Mi Oh, Hong Seok Park, Je Jong Kim, Du Geon Moon   +8 more
doaj   +1 more source