Results 71 to 80 of about 822,971 (285)

Abyssomicins—A 20-Year Retrospective View

open access: yesMarine Drugs, 2021
Abyssomicins represent a new family of polycyclic macrolactones. The first described compounds of the abyssomicin family were abyssomicin B, C, atrop-C, and D, produced by the marine actinomycete strain Verrucosispora maris AB-18-032, which was isolated ...
Hans-Peter Fiedler
doaj   +1 more source

Meteoritic Abundances of Fatty Acids and Potential Reaction Pathways in Planetesimals [PDF]

open access: yesIcarus, 2019, 319, 685-700, 2018
The origin of fatty acids on the prebiotic Earth is important as they likely formed the encapsulating membranes of the first protocells. Carbon-rich meteorites (i.e., carbonaceous chondrites) such as Murchison and Tagish Lake are well known to contain these molecules, and their delivery to the early planet by intense early meteorite bombardments ...
arxiv   +1 more source

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]

open access: yes, 2012
Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O.   +4 more
core   +5 more sources

An Efficient Thiol‐ene Mediated Protocol for Thiolated Peptide Synthesis and On‐Resin Diversification

open access: yesChemistry – A European Journal, EarlyView.
Herein, a sequential acyl‐thiol‐ene/S‐deacetylation protocol for selective installation of thiol residues onto synthetic peptides, on‐resin, is demonstrated. The hydrothiolation/S‐deacetylation protocol offers a novel synthetic tool for direct peptide conjugation on‐resin and for the preparation of novel disulfide containing neuropeptides displaying ...
Nikita Ostrovitsa   +5 more
wiley   +1 more source

Verrucosispora fiedleri sp. nov., an actinomycete isolated from a fjord sediment which synthesizes proximicins [PDF]

open access: yes, 2012
A novel filamentous actinobacterial organism, designated strain MG-37T, was isolated from a Norwegian fjord sediment and examined using a polyphasic taxonomic approach.
Ahmed, Lina   +9 more
core   +1 more source

A Direct Measurement of the Absolute Energies of Protonated Gly‐Pro‐Gly‐Gly Conformations Using Ion Mobility Spectrometry and Guided Ion Beam Tandem Mass Spectrometry

open access: yesChemPhysChem, EarlyView.
Relative energies of the cis and trans conformers of the protonated tetrapeptide, Gly‐Pro‐Gly‐Gly, selected by ion mobility spectrometry are measured using threshold collision‐induced dissociation. The trans conformation was found to be more stable than the cis conformation by 4.5 ± 2.5 kJ mol−1 at 0 K, a value in agreement with several levels of ...
Brandon C. Stevenson   +3 more
wiley   +1 more source

Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement. [PDF]

open access: yes, 2019
An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily ...
Delgado, Jose M   +5 more
core  

Hydrous Manganese Oxide Doped Gel Probe Sampler for Measuring In Situ Reductive Dissolution Rates. 1. Laboratory Development [PDF]

open access: yes, 2010
Reductive dissolution of redox-sensitive minerals such as manganese (Mn) oxides in natural sediments is an important mechanism for trace element mobilization into groundwater.
Farnsworth, Claire E., Hering, Janet G.
core   +2 more sources

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

open access: yesElectrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Glial Versus Neuronal Na+/K+‐ATPase in Activity‐Evoked K+ Clearance and Their Sensitivity to Elevated Extracellular K+

open access: yesGlia, EarlyView.
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen   +6 more
wiley   +1 more source

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