Results 51 to 60 of about 2,830 (156)

Multi‐Omics Analysis Reveals Disturbances of Purine Metabolism and Glutamate Metabolism in the Hippocampus of Lipopolysaccharide‐Induced Mouse Model of Depression

open access: yesBrain and Behavior, Volume 15, Issue 5, May 2025.
The study focused on a mouse model of depression induced by lipopolysaccharides (LPS) and employed innovative multi‐omics approaches, including two‐dimensional gel electrophoresis (2‐DE) for proteomics, liquid chromatography–mass spectrometry (LC–MS) for metabolomics, and real‐time polymerase chain reaction (PCR) microarray technology to analyze the ...
Wen‐Wen Li   +10 more
wiley   +1 more source

Characteristics of GABAergic and cholinergic neurons in perinuclear zone of mouse supraoptic nucleus [PDF]

open access: yes, 2015
The perinuclear zone (PNZ) of the supraoptic nucleus (SON) contains some GABAergic and cholinergic neurons thought to innervate the SON proper. In mice expressing enhanced green fluorescent protein (eGFP) in association with glutamate decarboxylase (GAD ...
Armstrong, W. E.   +3 more
core   +1 more source

Proteome Reprogramming and Acquired Stress Tolerance in Potato Cells Exposed to Acute or Stepwise Water Deficit

open access: yesPlant, Cell &Environment, Volume 48, Issue 5, Page 2875-2894, May 2025.
ABSTRACT Water deficit negatively impacts crop productivity and quality. Plants face these challenges by adjusting biological processes and molecular functions according to the intensity and duration of the stress. The cultivated potato (Solanum tuberosum) is considered sensitive to water deficit, thus breeding efforts are needed to enhance its ...
Elisa Cappetta   +11 more
wiley   +1 more source

Preparation of Neurospora crassa mitochondria [PDF]

open access: yes, 1978
The fungus Neurospora crassa represents a eukaryotic cell with high biosynthetic activities. Cell mass doubles in 2-4 hr during expone ntial growth , even in simple salt media with sucrose as the sole carbon source. The microorgani sm forms a mycelium of
Jacki   +11 more
core   +2 more sources

Metabolic Reprogramming in Stromal and Immune Cells in Rheumatoid Arthritis and Osteoarthritis: Therapeutic Possibilities

open access: yesEuropean Journal of Immunology, Volume 55, Issue 4, April 2025.
Immune cells and stromal cells undergo metabolic reprogramming in both rheumatoid and osteoarthritis. This review summarises current evidence on the metabolic changes within and the crosstalk between immune and stromal cells in these diseases. In addition, we explore the therapeutic potential of targeting metabolic processes for the treatment of ...
Órlaith C. Henry, Luke A. J. O'Neill
wiley   +1 more source

Gut microbiota role in dietary protein metabolism and health-related outcomes: The two sides of the coin [PDF]

open access: yes, 2016
Background: Human gut bacteria can synthesize proteinogenic amino acids and produce a range of metabolites via protein fermentation, some known to exert beneficial or harmful physiological effects on the host.
Beaumont, Martin   +5 more
core   +3 more sources

Microbial Melatonin Production Improves Plant Metabolic Function in Short‐Term Climate‐Induced Stresses

open access: yesJournal of Pineal Research, Volume 77, Issue 3, April 2025.
ABSTRACT Climate change, specifically high temperatures, can reduce soil moisture and cause hypersaline conditions, which creates an unsustainable agro‐production system. Microbial symbionts associated with plants relinquish stressful conditions by producing stress‐protecting substances.
Eun‐Hae Kwon   +9 more
wiley   +1 more source

Compatible Solute Synthesis and Import by the Moderate Halophile Spiribacter salinus: Physiology and Genomics [PDF]

open access: yes, 2018
Members of the genus Spiribacter are found worldwide and are abundant in ecosystems possessing intermediate salinities between seawater and saturated salt concentrations.
Bremer, Erhard   +5 more
core   +1 more source

Genomic data mining reveals the transaminase repertoire of Komagataella phaffii (Pichia pastoris) strain GS115 and supports a systematic nomenclature [PDF]

open access: yes, 2020
Transaminases are an industrially important class of enzyme, due to their ability to catalyse amination reactions for production of chiral amines, and are key building blocks of small molecule pharmaceuticals.
Cardós-Elena, RP   +2 more
core  

The Emerging Role of Altered D-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies [PDF]

open access: yes, 2018
Besides D-serine, another D-amino acid with endogenous occurrence in the mammalian brain, D-aspartate, has been recently shown to influence NMDA receptor (NMDAR)-mediated transmission.
Alessandro Bertolino   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy