Results 41 to 50 of about 4,514 (173)

Decreased Prevalence of Plasmodium Falciparum Resistance Markers to Amodiaquine Despite its wide Scale use as ACT Partner Drug in Zanzibar. [PDF]

open access: yes, 2012
Zanzibar has recently undergone a rapid decline in Plasmodium falciparum transmission following combined malaria control interventions with artemisinin-based combination therapy (ACT) and integrated vector control.
Björkman, Anders   +7 more
core   +4 more sources

Synthesis and antiplasmodial activity of regioisomers and epimers of second-generation dual acting ivermectin hybrids

open access: yesScientific Reports, 2022
With its strong effect on vector-borne diseases, and insecticidal effect on mosquito vectors of malaria, inhibition of sporogonic and blood-stage development of Plasmodium falciparum, as well as in vitro and in vivo impairment of the P.
Lovepreet Singh   +4 more
doaj   +1 more source

Macromolecular 4-aminoquinoline compounds as potential antimalarial drugs [PDF]

open access: yes, 2011
4-Aminoquinolines have a long and successful history as antimalarials as they have provided a number of useful antimalarials. P. falciparum, a causative organism of the most deadly form of human malaria, is generally slow to develop resistance to these ...
Aderibigbe, Atim Blessing
core  

Epidemiological distribution of Plasmodium falciparum drug resistance in Brazil and its relevance to the treatment and control of malaria

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
With the use of a simple formulary, field by health agents was ewstablished a monitoring programme for responses of P. falciparum to the antimalarial drugs.
José Maria de Souza
doaj   +1 more source

Susceptibility of Colombian Plasmodium falciparum isolates to 4-aminoquinolines and the definition of amodiaquine resistance in vitro

open access: yesMemorias do Instituto Oswaldo Cruz, 2006
There are wide variations in the threshold used to define in vitro resistance of Plasmodium falciparum to amodiaquine (AQ), probably due to differences in methodology and interpretation. In vitro susceptibility data of Colombian P.
Diego F Echeverry   +3 more
doaj   +1 more source

In vitro activity of immunosuppressive drugs against Plasmodium falciparum [PDF]

open access: yes, 2014
Background Solid organ transplant recipients are particularly vulnerable for infectious diseases due to prolonged immunosuppressive treatment. Residents of endemic regions and travellers may be exposed to malaria and may, therefore, require prolonged ...
Felix Loetsch   +6 more
core   +2 more sources

New 4-aminoquinoline-based cholinesterase inhibitors

open access: yes, 2021
Medical treatment of Alzheimer’s disease (AD) and related dementias is mainly based on improving the level of the neurotransmitter acetylcholine in the brain by inhibiting the enzymes involved in acetylcholine breakdown, acetylcholinesterase and butyrylcholinesterase.
Bosak, Anita   +3 more
openaire   +3 more sources

THE ACTIVITY OF 4-AMINOQUINOLINE AGAINST PLASMODIUM FALCIPARUM IN SOUTHERN IRAN

open access: yesIranian Journal of Public Health, 1973
The resistance of Plasmodium falciparum to 4-amioquinolines has been confirmed in parts of South America such as Venezuela, Colombia, Brazil and Panama since 1961. During 1968-1970, 147 P.
AV. Manouchehri   +2 more
doaj  

In vitro Dissolution Profile at Different Biological pH Conditions of Hydroxychloroquine Sulfate Tablets Is Available for the Treatment of COVID-19

open access: yesFrontiers in Molecular Biosciences, 2021
Hydroxychloroquine sulfate is one of an extensive series of 4-aminoquinolines with antimalarial activity. Moreover, it is used for the treatment of rheumatoid arthritis.
Thirupathi Dongala   +8 more
doaj   +1 more source

Amodiaquine failure associated with erythrocytic glutathione in Plasmodium falciparum malaria [PDF]

open access: yes, 2007
Objective To establish the relationship between production of glutathione and the therapeutic response to amodiaquine (AQ) monotherapy in Plasmodium falciparum non-complicated malaria patients.
Lina Zuluaga   +4 more
core   +1 more source

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