Results 181 to 190 of about 32,447,375 (296)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

4-D Reconstruction of Fetal Left Ventricle From Echocardiography via 2.5-D Radial Segmentation and Graph-Fourier Reconstruction. [PDF]

IEEE Trans Med Imaging
Hasan MK, Wang Q, Shahard H, Iijima L, Ruseckaite N, Luo Y, Scharnreitner I, Tulzer A, Liu B, Yang G, Yap CH.   +10 more
europepmc   +1 more source

High-resolution 4-D acquisition of freely swimming human sperm cells without staining. [PDF]

Sci Adv, 2020
Dardikman-Yoffe G, Mirsky SK, Barnea I, Shaked NT.   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

A case of suspected 2, 4-D ethyl ester poisoning mimicking organophosphate toxicity: a diagnostic and therapeutic challenge. [PDF]

Acute Crit Care
Rao JK, Chilakapati S.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Dermal elastin and collagen in systemic sclerosis. Effect of D-penicillamine treatment

, 1989
Skin biopsies from 4 systemic sclerosis (SSc) patients, 6 SSc patients treated with D-penicillamine (from 8 to 60 months) and 4 normal subjects were analyzed by light and electron microscopy.
Quaglino D., Guerra D., Ronchetti IP., Vincenzi D., Manzini E., Manzini C. U., Canossi B.   +6 more
core  

An image encryption scheme using 4-D chaotic system and cellular automaton. [PDF]

Sci Rep
Al-Dayel I, Nadeem MF, Khan MA, Abraha BS.   +3 more
europepmc   +1 more source

Corrigendum: Effect of the protease plasmin on C. elegans hyperactive DEG/ENaC channels MEC-4(d) and UNC-8(d). [PDF]

MicroPubl Biol, 2021
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source