Results 171 to 180 of about 26,058,575 (297)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
[Early Australian homestead] [picture] /
Rex Nan Kivell Collection NK10164/4.; Exhibited: Bridging the Distance, National Library of Australia, 5 March 2008 - 15 June 2008 AuCNL ...
Cooper, Duncan, 1813 or 4-1904.
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Dermal elastin and collagen in systemic sclerosis. Effect of D-penicillamine treatment
Skin biopsies from 4 systemic sclerosis (SSc) patients, 6 SSc patients treated with D-penicillamine (from 8 to 60 months) and 4 normal subjects were analyzed by light and electron microscopy.
Quaglino D. +6 more
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Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
High-resolution 4-D acquisition of freely swimming human sperm cells without staining. [PDF]
Dardikman-Yoffe G +3 more
europepmc +1 more source
Ages of D/d,n/He sup 3 and T/d,n/He sup 4 neutrons in water and tungsten-water mixtures
Ages for D-D and D-T neutrons in water and tungsten-water ...
Shook, D. F. +2 more
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The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Purpose: To compare the marginal fit and accuracy of definitive crowns printed with (1) Sprintray Ceramic Crown using Sprintray’s DLP Pro55s printer to that of (2) milled and sintered IPS e.max CAD (Ivoclar Vivadent) lithium disilicate crowns milled via ...
Faddoul, Alexandre J
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