Results 71 to 80 of about 26,058,575 (297)
Enriched KEGG pathway of DEGs in lariciresinol-4-β-D-glucopyranoside treatment.
, 2017 Enriched KEGG pathway of DEGs in lariciresinol-4-β-D-glucopyranoside treatment.
Zhihong Jiang (50021) +4 more
core +1 more source
Results in ChemistryContinuous evolution in bacterial strains confines utility of frontline antibacterial agents due to development of multiple resistance mechanisms. Especially gram-negative multidrug bacterial resistance is foremost important topic of concern. The current
Satish Bhavsar +10 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Synthesis of 4-Diphosphocytidyl-2-C-methyl-d-erythritol and 2-C-Methyl-d-erythritol-4-phosphate
, 2016 2-C-Methyl-d-erythritol 4-phosphate (MEP, 2) and 4-diphosphocytidyl-2-C-methyl-d-erythritol (CDPME, 3) are metabolites in the MEP pathway for biosynthesis of isoprenoid compounds in bacteria, plant chloroplasts, and algae.
C. Dale Poulter (641717) +1 more
core +1 more source
NUT-charged black holes in matter-coupled N=2, D=4 gauged supergravity [PDF]
, 2012 Using the results of arXiv:0804.0009, where all timelike supersymmetric backgrounds of N=2, D=4 matter-coupled supergravity with Fayet-Iliopoulos gauging were classified, we construct genuine nut-charged BPS black holes in AdS_4 with nonconstant moduli ...
D. Klemm, M. Colleoni
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Preeclampsia risk, maternal 25-hydroxyvitamin D concentration, and variation in vitamin D metabolism pathway genes [PDF]
, 2016 OBJECTIVE: Our objectives were to study the relationships between 25-hydroxyvitamin D (25(OH)D) and preeclampsia risk, maternal genetic variation in 3 vitamin D metabolism genes (GC, CYP27B1, VDR) and preeclampsia risk, and variation in the same genes ...
Baca, Katharyn
core
, 2000 A mutant of Mycobacterium smegmatis has been isolated that is simultaneously resistant to both D-cycloserine (D-CS) and vancomycin. Genetic complementation with a PBP4 homolog restores sensitivity to both drugs.
Connell, ND +13 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Diagnosis and Treatment of Clonal Myeloproliferative Neoplasms with Eosinophilia
Клиническая онкогематология, 2020 Aim. Based on our own materials to characterize the clinical manifestations of hypereosinophilic states distinguishing between reactive eosinophilia (RE), clonal myeloproliferative neoplasms with eosinophilia (MPN-eo), and myeloproliferative variant of ...
Irina Semenovna Nemchenko +6 more
doaj +1 more source