Results 91 to 100 of about 32,447,375 (296)

Intermediate Results of Prospective, Randomized, Comparative Study of NHL BFM-90 and СНОЕР Efficacy in Primary ALK-Positive Anaplastic Large-Cell Lymphoma

Клиническая онкогематология, 2020
Aim. To compare NHL BFM-90 and CHOEP efficacy in adult patients with ALK-positive anaplastic large-cell lymphoma (ALK+ ALCL). Materials & Methods. Within the period from June 2014 to December 2019 the prospective randomized comparative study at the ...
Liliya Gamilevna Gorenkova, S. K. Kravchenko, E. E. Klebanova, A. M. Kovrigina, K. A. Sychevskaya, E. G. Gemdzhian, E. S. Nesterova, Ya. K. Mangasarova, A. V. Misyurin, Yu. V. Sidorova, T. N. Obukhova   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Response-Adapted Strategy in the Treatment of Primary Mediastinal Large B-Cell Lymphoma: Results of a Prospective Single-Center Clinical Trial

Клиническая онкогематология
BACKGROUND. Up to now, neither the optimal treatment regimen for primary mediastinal large B-cell lymphoma (PMBCL), nor poor/favorable prognostic factors for risk stratification at the disease onset have been found.
Yana Konstantinovna Mangasarova, R. R. Abdurashidova, A. U. Magomedova, O. V. Margolin, E. S. Nesterova, L. G. Gorenkova, M. O. Bagova, E. A. Fastova, D. S. Belkina, A. M. Kovrigina, N. G. Gabeeva, D. A. Koroleva, S. K. Kravchenko, Yu. A. Chabaeva, E. E. Zvonkov   +14 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Stereoselective synthesis of 4-amino-3-hydroxy-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-4-carboxylic acid, a conformationally constrained analogue of aspartic acid

, 2007
An alternative synthesis of 4-amino-3-hydroxy-4,5,6,6a-tetrahydro-3aH- cyclopenta[d]isoxazole-4-carboxylic acid, a conformationally constrained analogue of aspartic acid, is described.
G. Roda, D. Arosio, A. Pinto, C. De Micheli, Carlo De Micheli, Andrea Pinto, Paola Conti, Lucia Tamborini, P. Conti, L. Tamborini, Dario Arosio, Gabriella Roda   +11 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CONFORMATIONAL STUDIES AND STEREOCHEMICAL ASSIGNMENTS OF THE LACTARANE SESQUITERPENES FUROSCROBICULIN-D AND BLENNIN-D

, 1994
Two lactarane, sesquiterpenes, furoscrobiculin D and blennin D, previously isolated from the mushrooms Lactarius scrobiculatus and Lactarius blennius, respectively, have been submitted to conformational analysis by molecular mechanics. The results of the
VIDARI, GIOVANNI, L. GARLASCHELLI, TOMA, LUCIO, G. VIDARI, D. COLOMBO, L. TOMA   +5 more
core   +1 more source

Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype [PDF]

, 2012
Background: Neuropsychiatric symptoms such as psychosis are prevalent in patients with probable Alzheimer's disease (AD) and are associated with increased morbidity and mortality.
Lopez, OL, Shofer, J, Sweet, RA, Tsuang, D, Weamer, EA, Kamboh, MI, Millard, SP, Li, E, Christie, D, DeMichele-Sweet, MA   +9 more
core   +1 more source

Thrombotic and Hemorrhagic Complications in the Treatment of Acute Lymphoblastic Leukemia with L-Asparaginase

Клиническая онкогематология, 2018
The article provides a literature review on the use of the L-asparaginase (ASP) in acute lymphoblastic leukemia (ALL) and describes two clinical cases.
Gennadii Martinovich Galstyan, O. A. Polevodova, A. V. Bazhenov, V. V. Troitskaya, O. A. Gavrilina, D. G. Gitel’zon, A. E. Vasil’ev, E. N. Parovichnikova   +7 more
doaj   +1 more source

4-D Micro-CT of the Mouse Heart

Molecular Imaging, 2005
Purpose: Demonstrate noninvasive imaging methods for in vivo characterization of cardiac structure and function in mice using a micro-CT system that provides high photon fluence rate and integrated motion control. Materials and Methods: Simultaneous cardiac- and respiratory-gated micro-CT was performed in C57BL/6 mice during constant intravenous ...
Cristian T. Badea, Boma Fubara, Laurence W. Hedlund, G. Allan Johnson   +3 more
openaire   +3 more sources